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V. CURRICULUM IN INGLESE

CURRICULUM VITAE ET STUDIORUM Professor Emmanuele A. JANNINI, MD, OMRI, KSG, KHS       Emmanuele Angelo Francesco Jannini (shortly: Emmanuele A. Jannini), Full Professor of Endocrinology, Andrology and Sexual Medicine at the Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy, was born in Milan, Italy on April 22, 1960.    From 1979 to 1986, he was a fellow at the Institute of Histology and General Embryology (Prof. M. Stefanini) and at the Chair of Andrology of the V Institute of Clinical Medicine (Prof. A. Isidori), University of Rome La Sapienza. In 1986, he received his Medical Doctor degree (with honors), presenting an experimental thesis entitled “New endocrine aspects of idiopathic impotence”, and in 1994, he specialized (with honors) in endocrinology and andrology (thesis: “Role of thyroid hormones in testicular ontogenesis”).  From 1988 to 1989 he was a PhD fellow in Endocrinology at the University of L’Aquila. In 1990, he was made Assistant Professor of Endocrinology at the Medical School of the University of L’Aquila. Subsequently, in 2000, he was appointed Associate Professor of Endocrinology and Sexology at the Medical School of the University of L’Aquila, and in 2007, Founder and Coordinator of the School of Sexology at the Faculty of Psychology of the University of L’Aquila. In 2010, he received a full professorship in Endocrinology. In 2014 he was appointed Full Professor of Endocrinology, Andrology, and Sexual Medicine at the Department of Systems Medicine of the University of Rome Tor Vergata, where he holds the first, and unique, course of Endocrinology and Medical Sexology (ENDOSEX) in the Italian universities for the students of the English Medical School. Finally, he built with the colleagues of the Rome Sapienza University the first Inter-Universities (Universities of Rome Tor Vergata and Sapienza) 2yrs Master Course in Clinical Psychosexology, where he is lecturing, as full Professor, on Psychoneuroendocrinology and Medical Sexology. From 2020, he has been also appointed Dean of the new School of Medicine at the Kore University of Enna, Italy.   Professor Jannini has had numerous experiences abroad: from 1990 to 1991 he was a guest researcher at the Clinical Endocrinology Branch (Chief, Dr J. Robbins), NIDDK, National Institutes of Health (Bethesda, MD, USA), working in the Laboratory of Molecular Endocrinology (Dr V.M. Nikodem). This was followed by an appointment (1992 and 1993) as exchange scientist at the Genetics and Biochemistry Branch (Chief, Dr D. Camerini-Otero), NIDDK, National Institutes of Health (Bethesda, MD, USA), where he worked in the genetics laboratories (Dr J.E. Rall). From 2007 to 2011, he lectured at St Catherine’s College, Oxford (UK) on summer courses organized by the European Academy of Sexual Medicine. Professor Jannini is Visiting Professor of Andrology or Urology in the following Universities: First Affiliated Hospital, Sun Yat-sen University School of Medicine (Guanghzhou); First Affiliated Hospital, Anhui Medical Universiy (Hefei); Shanghai General Hospital and Department of Urology, Shanghai Jiao Tong University, School of Medicine (Shanghai), from 2018 to 2021 and Academic Advisor of the First Teaching Hospital of Tianjing University of Traditional Chinese Medicine.   Emmanuele A. Jannini has received various awards in the course of his career: the Valerio Monesi Fellowship for Research in Reproduction (1987), the Becton Dickinson Award of the Italian Society of Endocrinology (1992), the First Award of the European Academy of Andrology (2000), the prize for the best Special Issue of the Journal of Endocrinological Investigation (2004), and the XXV Ottorino Rossi Award from the “Mondino” Neurologic Insitute, Pavia (2014).    Prof. Jannini is President of the Italian Academy for Couple Health, General Secretary of the of the Committee of the Italian Full Professors of Endocrinology, Past General Secretary of the Italian Society of Endocrinology, Past President of the Italian Society of Andrology and Sexual Medicine, a past member of the Standard Committee of the International Society for Sexual Medicine, chairman of the Education Committee of the European Academy of Andrology, past member of the University Committee of the International Society for Sexual Medicine Open Online University. Moreover, he is the Italian representative of the Section of Endocrinology within the UEMS (Union Européenne des Médecins Spécialistes) and representative of that section in the Multidisciplinary Joint Committee on Sexual Medicine (MJCSM) of the UEMS. In 2018 he has been elected President of the MJCSM, being the first endocrinologist with that duty aiming to provide to medical doctors competency certification in Sexual Medicine. Finally, he has served the European Medicines Agency, London, UK, as member of the Scientific Advisory Group for endocrinology and diabetes. He is has been editor of the section "Controversies in Sexual Medicine" of the Journal of Sexual Medicine (<>  on 2007, 2008, 2011, and 2012) and is currently Associate Editor of the Journal of Endocrinological Investigation and Sexual Medicine Reviews, and a member of the Editorial Boards of Andrology, Folia Biologica, Endocrine, and Journal of Mind and Medical Sciences. He is the editor of Italian and international textbooks of andrology and sexual medicine, published and translated in different languages (English, Italian, Portuguese, Japanese, Chinese Mandarin). He is Editor-in-Chief of the new Springer Textbook Series <> and Co-Editor of the multi-volume handbook Springer series on Endocrinology.   Prof. Jannini’s scientific activity is reflected in his > 255 full papers published in peer-reviewed international journals (total impact factor: >600; cited >14000 times; H-index: 57, according to Scopus and 67, according to Google scholar). His main research interests are sexual medicine and andrology (erectile dysfunction and subcellular localization of type 5 phosphodiesterase; pathophysiology of premature ejaculation; functional anatomy of female orgasm) and endocrinology of reproduction and sexuality, particularly testosterone and thyroid pathophysiology (role of sexual activity in the control of the hypothalamus-pituitary-testiscular axis; molecular localization and the role of the nuclear thyroid hormone receptor in the male genital tract). He conducts his research in endocrinology, andrology and sexual medicine both from a clinical and a basic perspective employing molecular, clinical and psychometric tools. On the strength of his publications, he is listed in the top three authors in the field of premature ejaculation (Hui J et al. Int J Impot Res, 2020), in the top ten authors in the field of erectile dysfunction (Hui J et al. Int J Impot Res, 2019), and, on the basis of his citation metrics, in the list of worldwide 100.000 scientists (Ioannidis JPA et al., Plos Biol, 2019), as well in the classification of the Top Italian Scientists (http://www.topitalianscientists.org). Finally, Prof. Jannini is active in promoting education in sexual medicine and public sexual health worldwide and  a recipient of several public and private research grants.   ADDRESS:   Chair of Endocrinology, Andrology, and Medical Sexology Department of Systems Medicine University of Rome Tor Vergata    Via Montpellier, 1 00133 Rome ITALY   eajannini@gmail.com emmanuele.jannini@uniroma2.it        10 BEST FULL PAPERS   1. E.A. JANNINI, M. OLIVIERI, S. FRANCAVILLA, A. GULINO, E. ZIPARO, M. D'ARMIENTO: Ontogenesis of the nuclear 3,5,3'-triiodothyronine receptor in the rat testis. Endocrinology, 126:2521-2526, 1990 2. E.A. JANNINI, T. MITSUHASHI, V.M. NIKODEM: Developmental expression of mRNAs from a rat c-erbA genomic locus. Biochem. Biophys.Res. Commun., 184:739-745, 1992 3. E.A. JANNINI, S. DOLCI, S. ULISSE, V.M. NIKODEM: Developmental regulation of the thyroid hormone receptor 1 mRNA expression in the rat testis. Mol. Endocrinol., 8:89-96, 1994 4. E.A. JANNINI, S. ULISSE, M. D’ARMIENTO: Thyroid hormone and male gonadal function. Endocrine Rev.,16:443-459, 1995 5. S. ULISSE, N. RUCCI, D. PIERSANTI, E. CAROSA, F.M. GRAZIANO, A. PAVAN, P. CEDDIA, M. ARIZZI, P. MUZI, L. GNESSI, M. D'ARMIENTO, E.A. JANNINI: Regulation by thyroid hormone of the expression of basement membrane components in rat prepubertal Sertoli cells. Endocrinology, 139:741-747, 1998 6. CAROSA, A. FANELLI, S. ULISSE, R. DI LAURO, E.J. RALL, E.A. JANNINI: Ciona intestinalis nuclear receptor 1: a new member of steroid/thyroid hormone receptor family. Proc. Natl. Acad. Sci. USA, 95:11152-11157, 1998 7. E.A. JANNINI, A. CRESCENZI, N. RUCCI, E. SCREPONI, E. CAROSA, A. DE MATTEIS, E. MACCHIA, G. D’AMATI, M. D’ARMIENTO: Ontogenetic pattern of thyroid hormone receptor expression in the human testis. J. Clin. Endocrinol. Metab., 85:3453-3457, 2000 8. C. CARANI, A.M. ISIDORI, A. GRANATA, E. CAROSA, M. MAGGI, A. LENZI, E.A. JANNINI: Multicenter study on the prevalence of sexual symptoms in male hypo- and hyperthyroid patients. J. Clin. Endocrinol. Metab., 90:6472-6479, 2005 9. E.A. JANNINI, O. BUISSON, A. RUBIO-CASILLAS: Beyond the G-spot: clitourethrovaginal complex anatomy in female orgasm. Nat. Rev. Urol., 11:531-538, 2014 10. E. COLONNELLO, G. CIOCCA, E. LIMONCIN, A. SANSONE, E.A. JANNINI: Redefining a sexual medicine paradigm: subclinical premature ejaculation as a new taxonomic entity. Nat Rev Urol. 2021 8:115-127   SPECIAL ISSUES AND EDITED BOOKS   1. E.A.JANNINI, C. McMAHON, M.  WALDINGER: Premature ejaculation. Berlin, Springer, 2012 2. E.A. JANNINI, A. LENZI (Guest Editors). Medical Sexology. J. Endocrinol. Invest., 26, Suppl. 3, 2003 3. A. LENZI, E.A. JANNINI, G. FORTI (Guest Editors). Erectile & Male Sexual Dysfunction. Int. J. Androl., 28, Suppl 2, 2005 4. E.A. JANNINI, H. PORST (Guest Editors). A Practical Approach to Premature Ejaculation. J. Sex. Med., 8, Suppl. 4, 2011 5. G. CORONA, E.A. JANNINI, M. MAGGI (Editors): Emotional, Physical and Sexual Abuse. Springer International Publishing, 2015 6. E.A. JANNINI, M. SIMONI (Guest Editors): Molecular Endocrinology of Sexual Behaviour. Mol. Cell. Endocrinol. – Special Issue 2018 7. E.A. JANNINI, A. SIRACUSANO: Sexual Dysfunctions in Mentally Ill Patients. Springer International Publishing, 2018 8. D.L. ROWLAND, E.A. JANNINI: Cultural Differences and the Practice of Sexual Medicine: A Guide for Sexual Health Practitioners. Springer International Publishing, 2020.     FULL PAPERS ON PEER REVIEWED INTERNATIONAL JOURNALS     1. Sansone A, Mollaioli D, Ciocca G, Limoncin E, Colonnello E, Jannini EA. Sexual dysfunction in men and women with diabetes: a mirror of their complications? Curr Diabetes Rev. 2021 Mar 8. doi: 10.2174/1573399817666210309104740.    2. Sansone A, Cignarelli A, Mollaioli D, Ciocca G, Limoncin E, Romanelli F, Balercia G, Jannini EA. The Social Aspects of Sexual Health: A Twitter-Based Analysis of Valentine’s Day Perception. Sexes 2021, 2(1), 50-59; https://doi.org/10.3390/sexes2010004 -   3. Ciocca G, Lingiardi V, Jannini EA. Letter to the Editor on "A Worldwide Internet Study Based on Implicit Association Test Revealed a Higher Prevalence of Adult Males' Androphilia than Ever Reported before". J Sex Med. 2021 Feb 6:S1743- 6095(21)00179-X. doi: 10.1016/j.jsxm.2021.01.176.    4. Peng J, Yang L, Liu L, Zhou R, Liu J, Li N, Li L, Jiang Y, Liu Y, Zhu Z, Zhang X, Shi G, Jain S, Jannini EA, Zhang Z.  Safety and Effectiveness of Dapoxetine On Demand in Chinese Men With Premature Ejaculation: Results of a Multicenter, Prospective, Open-Label Phase IV Study. Sex Med. 2021 Jan 30;9(2):100296. doi: 10.1016/j.esxm.2020.100296.   5. Nguyen Hoai B, Pham Minh Q, Nguyen Cao T, Sansone A, Colonnello E, Jannini EA. Data from 14,597 penile measurements of vietnamese men. Andrology. 2021 Jan 23. doi: 10.1111/andr.12978.   6. Colonnello E, Ciocca G, Limoncin E, Sansone A, Jannini EA. Redefining a sexual medicine paradigm: subclinical premature ejaculation as a new taxonomic entity. Nat Rev Urol. 2021 Feb;18(2):115-127. doi: 10.1038/s41585-020-00417-1.   7. Xi Y, Colonnello E, Ma G, Limoncin E, Ciocca G, Zhang H, Jannini EA, Zhang Y. Validity of Erectile Function Assessment Questionnaires in Premature Ejaculation Patients: A Comparative Study Between the Abridged Forms of the International Index of Erectile Function and Proposal for Optimal Cutoff Redefinition. J Sex Med. 2020 Dec 28:S1743-6095(20)31064-X. doi: 10.1016/j.jsxm.2020.11.018.   8. Caggiano C, Guida E, Todaro F, Bielli P, Mori M, Ghirga F, Quaglio D, Botta B, Moretti F, Grimaldi P, Rossi P, Jannini EA, Barchi M, Dolci S. Sempervirine inhibits RNA polymerase I transcription independently from p53 in tumor cells. Cell Death Discov. 2020 Oct 28;6(1):111. doi: 10.1038/s41420-020-00345-4.   9. Guo J, Wang F, Zhou Q, Geng Q, Gao Q, Zhang R, Zhang C, Xuan Z, Cai J, Bin B, Han Q, Guo B, Yan B, Zhang J, Colonnello E, Jannini EA. Safety and efficacy of traditional Chinese medicine, Qiaoshao formula, combined with dapoxetine in the treatment of premature ejaculation: An open-label, real-life, retrospective multicentre study in Chinese men. Andrologia. 2021 Feb;53(1):e13915. doi: 10.1111/and.13915.   10. Mollaioli D, Sansone A, Ciocca G, Limoncin E, Colonnello E, Di Lorenzo G, Jannini EA. Benefits of Sexual Activity on Psychological, Relational, and Sexual Health During the COVID-19 Breakout. J Sex Med. 2021 Jan;18(1):35-49. doi: 10.1016/j.jsxm.2020.10.008.   11. Fontanesi L, Marchetti D, Limoncin E, Rossi R, Nimbi FM, Mollaioli D, Sansone A, Colonnello E, Simonelli C, Di Lorenzo G, Jannini EA, Ciocca G. Hypersexuality and Trauma: a mediation and moderation model from psychopathology to problematic sexual behavior. J Affect Disord. 2021 Feb 15;281:631-637. doi: 10.1016/j.jad.2020.11.100.   12. Hou G, Gao M, Zhang L, Dun X, Zheng Y, Wang F, Yan F, Zheng W, Yin C, Yuan J, Zhang G, Meng P, Jannini EA, Yuan J. An Internally Validated Nomogram for Predicting the Likelihood of Improvement of Clinical Global Impression in Patients With Lifelong Premature Ejaculation Treated With Dapoxetine. J Sex Med. 2020 Dec;17(12):2341-2350. doi: 10.1016/j.jsxm.2020.09.005.   13. Sansone A, Aversa A, Corona G, Fisher AD, Isidori AM, La Vignera S, Limoncin E, Maggi M, Merico M, Jannini EA. Management of premature ejaculation: a clinical guideline from the Italian Society of Andrology and Sexual Medicine (SIAMS). J Endocrinol Invest. 2020 Oct 30. doi: 10.1007/s40618-020-01458-4.   14. Limoncin E, Solano C, Ciocca G, Mollaioli D, Colonnello E, Sansone A, Nimbi FM, Simonelli C, Tambelli R, Jannini EA. Can Physical and/or Sexual Abuse Play a Role in the Female Choice of a Partner? A Cross-Sectional, Correlational Pilot Study. Int J Environ Res Public Health. 2020 Sep 21;17(18):E6902. doi: 10.3390/ijerph17186902.   15. Cignarelli A, Sansone A, Caruso I, Perrini S, Natalicchio A, Laviola L, Jannini EA, Giorgino F. Diabetes in the Time of COVID-19: A Twitter-Based Sentiment Analysis. J Diabetes Sci Technol. 2020 Aug 7:1932296820945297. doi: 10.1177/1932296820945297. Online ahead of print.    16. Moscatelli A, Nimbi FM, Ciotti S, Jannini EA. Haptic and Somesthetic Communication in Sexual Medicine. Sex Med Rev. 2020 Jul 17:S2050-0521(20)30047-0. doi: 10.1016/j.sxmr.2020.02.003. Online ahead of print   17. Sansone A, Mollaioli D, Ciocca G, Limoncin E, Colonnello E, Vena W, Jannini EA. Addressing male sexual and reproductive health in the wake of COVID-19 outbreak. J Endocrinol Invest. 2020 Jul 13:1-9. doi: 10.1007/s40618-020-01350-1. Online ahead of print.    18. Cesarini V, Guida E, Campolo F, Crescioli C, Di Baldassarre A, Pisano C, Balistreri CR, Ruvolo G, Jannini EA, Dolci S. Type 5 phosphodiesterase (PDE5) and the vascular tree: From embryogenesis to aging and disease. Mech Ageing Dev. 2020 Jul 3;190:111311. doi: 10.1016/j.mad.2020.111311. Online ahead of print.    19. Ciocca G, Rossi R, Collazzoni A, Gorea F, Vallaj B, Stratta P, Longo L, Limoncin E, Mollaioli D, Gibertoni D, Santarnecchi E, Pacitti F, Niolu C, Siracusano A, Jannini EA, Di Lorenzo G. The impact of attachment styles and defense mechanisms on psychological distress in a non-clinical young adult sample: A path analysis. J Affect Disord. 2020 Aug 1;273:384-390. doi: 10.1016/j.jad.2020.05.014.    20. Pizzocaro A, Vena W, Condorelli R, Radicioni A, Rastrelli G, Pasquali D, Selice R, Ferlin A, Foresta C, Jannini EA, Maggi M, Lenzi A, Pivonello R, Isidori AM, Garolla A, Francavilla S, Corona G; King, Klinefelter ItaliaN Group.Testosterone treatment in male patients with Klinefelter syndrome: a systematic review and meta-analysis.. J Endocrinol Invest. 2020 Jun 21. doi: 10.1007/s40618-020-01299-1   21. Corona G, Baldi E, Isidori AM, Paoli D, Pallotti F, De Santis L, Francavilla F, La Vignera S, Selice R, Caponecchia L, Pivonello R, Ferlin A, Foresta C, Jannini EA, Lenzi A, Maggi M, Lombardo F. SARS-CoV-2 infection, male fertility and sperm cryopreservation: a position statement of the Italian Society of Andrology and Sexual Medicine (SIAMS) (Società Italiana di Andrologia e Medicina della Sessualità). J Endocrinol Invest. 2020 May 27:1-5. doi: 10.1007/s40618-020-01290-w.   22. Isidori AM, Jannini EA, Lenzi A, Ghigo E; Board of Full Professors in Endocrinology, Directors of the Endocrinology, Metabolic Disorders Residency Program. The Italian Endo-COVID-19. Our response to the emergency. J Endocrinol Invest. 2020 Jul;43(7):1039-1041. doi: 10.1007/s40618-020-01279-5.   23. Corona G, Sansone A, Pallotti F, Ferlin A, Pivonello R, Isidori AM, Maggi M, Jannini EA. People smoke for nicotine, but lose sexual and reproductive health for tar: a narrative review on the effect of cigarette smoking on male sexuality and reproduction. J Endocrinol Invest. 2020 Apr 22. doi: 10.1007/s40618-020-01257-x.   24. Aversa A, Jannini EA. COVID-19, or the triumph of monogamy? Minerva Endocrinol. 2020 Apr 9. doi: 10.23736/S0391-1977.20.03207-1.   25. Carosa E, Sansone A, Jannini EA. MANAGEMENT OF ENDOCRINE DISEASE: Female sexual dysfunction for the endocrinologist. Eur J Endocrinol. 2020 Apr 1:EJE-19-0903.R1. doi: 10.1530/EJE-19-0903.    26. Corona G, Jannini EA. Diffusion tensor imaging: A new valuable method for understanding male sexual functioning. Andrology. 2020 Mar;8(2):266-267. doi: 10.1111/andr.12768.   27. Mollaioli D, Ciocca G, Limoncin E, Di Sante S, Gravina GL, Carosa E, Lenzi A, Jannini EA. Lifestyles and sexuality in men and women: the gender perspective in sexual medicine. Reprod Biol Endocrinol. 2020 Feb 17;18(1):10. doi: 10.1186/s12958-019-0557-9.   28. Ciocca G, Robilotta A, Fontanesi L, Sansone A, D'Antuono L, Limoncin E, Nimbi F, Simonelli C, Di Lorenzo G, Siracusano A, Jannini EA. Sexological Aspects Related to Tinder Use: A Comprehensive Review of the Literature.ex Med Rev. 2020 Feb 20:S2050-0521(20)30001-9. doi: 10.1016/j.sxmr.2019.12.004.   29. Monteleone P, Amore M, Cabassi A, Clerici M, Fagiolini A, Girardi P, Jannini EA, Maina G, Rossi A, Vita A, Siracusano A. Attitudes of Italian Psychiatrists Toward the Evaluation of Physical Comorbidities and Sexual Dysfunction in Patients With Schizophrenia. Implications for Clinical Practice. Front Psychiatry. 2019 Nov 20;10:842. doi: 10.3389/fpsyt.2019.00842. eCollection 2019. PMID:    31824349   30. Burgio G, Giammusso B, Calogero AE, Mollaioli D, Condorelli RA, Jannini EA, La Vignera S. Evaluation of the Mistakes in Self-Diagnosis of Sexual Dysfunctions in 11,000 Male Outpatients: A Real-Life Study in An Andrology Clinic. J Clin Med. 2019 Oct 14;8(10). pii: E1679. doi: 10.3390/jcm8101679.   31. Ciocca G, Zauri S, Limoncin E, Mollaioli D, D'Antuono L, Carosa E, Nimbi FM, Simonelli C, Balercia G, Reisman Y, Jannini EA. Attachment Style, Sexual Orientation, and Biological Sex in their Relationships With Gender Role. Sex Med. 2020 Mar;8(1):76-83. doi: 10.1016/j.esxm.2019.09.001.   32. Cesarini V, Pisano C, Rossi G, Balistreri CR, Botti F, Antonelli G, Ruvolo G, Jannini EA, Dolci S. Regulation of PDE5 expression in human aorta and thoracic aortic aneurysms. Sci Rep. 2019 Aug 21;9(1):12206. doi: 10.1038/s41598-019-48432-6.   33. Bisegna C, Gravina GL, Pierconti F, Martini M, Larocca L, Rossi P, Grimaldi P, Dolci S, Di Stasi S, Jannini EA. Regulation of PDE5 expression in normal prostate, benign prostatic hyperplasia, and adenocarcinoma. Andrology. 2020 Mar;8(2):427-433. doi: 10.1111/andr.12695.   34. Sansone A, Cignarelli A, Ciocca G, Pozza C, Giorgino F, Romanelli F, Jannini EA. The Sentiment Analysis of Tweets as a New Tool to Measure Public Perception of Male Erectile and Ejaculatory Dysfunctions. Sex Med. 2019 Dec;7(4):464-471. doi: 10.1016/j.esxm.2019.07.001.    35. Aversa A, Jannini EA. COVID-19, or the triumph of monogamy? Minerva Endocrinol. 2020 Apr 9. doi: 10.23736/S0391-1977.20.03207-1. Online ahead of print. PMID: 32270992   36. Jannini EA, Reisman Y. Medicine Without Sexual Medicine Is Not Medicine: An MJCSM and ESSM Petition on Sexual Health to the Political and University Authorities. J Sex Med. 2019 Jun;16(6):943-945. doi: 10.1016/j.jsxm.2019.04.001.   37. Miranda EP, Taniguchi H, Cao DL, Hald GM, Jannini EA, Mulhall JP. Application of Sex Aids in Men With Sexual Dysfunction: A Review. J Sex Med. 2019 Jun;16(6):767-780. doi: 10.1016/j.jsxm.2019.03.265.    38. Todaro F, Campolo F, Barrios F, Pellegrini M, Di Cesare S, Tessarollo L, Rossi P, Jannini EA, Dolci S. Regulation of Kit Expression in Early Mouse Embryos and ES Cells. Stem Cells. 2019 Mar;37(3):332-344. doi: 10.1002/stem.2960.    39. Jannini EA, Droupy S. Needs and Expectations of Patients with Erectile Dysfunction: An Update on Pharmacological Innovations in Phosphodiesterase Type 5 Inhibition with Focus on Sildenafil.  Sex Med. 2019 Mar;7(1):1-10. doi: 10.1016/j.esxm.2018.10.005.    40. Maseroli E, Scavello I, Rastrelli G, Limoncin E, Cipriani S, Corona G, Fambrini M, Magini A, Jannini EA, Maggi M, Vignozzi L. Outcome of Medical and Psychosexual Interventions for Vaginismus: A Systematic Review and Meta-Analysis. J Sex Med. 2018 Dec;15(12):1752-1764. doi: 0.1016/j.jsxm.2018.10.003.    41. Limoncin E, Gravina GL, Lotti F, Maseroli E, Ciocca G, Corona G, Maggi M, Reisman Y, Balercia G, Lenzi A, Jannini EA. The Masturbation Erection Index (MEI): validation of a new psychometric tool, derived from the six-item version of the International Index of Erectile Function (IIEF-6) and from the Erection Hardness Score (EHS), for measuring erectile function during masturbation. BJU Int. 2019 Mar;123(3):530-537. doi: 10.1111/bju.14560.    42. Mollaioli D, Di Sante S, Limoncin E, Ciocca G, Gravina GL, Maseroli E, Fanni E, Vignozzi L, Maggi M, Lenzi A, Jannini EA. Validation of a Visual Analogue Scale to measure the subjective perception of orgasmic intensity in females: The Orgasmometer-F. PLoS One. 2018 Aug 29;13(8):e0202076. doi: 0.1371/journal.pone.0202076. eCollection 2018.   43. Trimarchi F, Jannini EA. A Flemish Kermis by Peeter Baltens: fashion or Peyronie's disease? J Endocrinol Invest. 2018 Aug 9. doi: 10.1007/s40618-018-0933-x. [Epub ahead of print] PMID: 30094744   44. Mulhall JP, Giraldi A, Hackett G, Hellstrom WJG, Jannini EA, Rubio-Aurioles E, Trost L, Hassan TA. The 2018 Revision to the Process of Care Model for Evaluation of Erectile Dysfunction. J Sex Med. 2018 Jul 26. pii: S1743-6095(18)31049-X. doi: 10.1016/j.jsxm.2018.06.005. [Epub ahead of print]. PMID:  30057280   45. Jannini EA, Nappi RE. Couplepause: A New Paradigm in Treating Sexual Dysfunction During Menopause and Andropause. Sex Med Rev. 2018 Jul;6(3):384-395. doi: 10.1016/j.sxmr.2017.11.002. Epub 2018 Jan 19. Review. PMID:    29371146   46. Jannini EA, Simoni M. Editorial - Sex goes molecular! Mol Cell Endocrinol. 2018 May 15;467:1-2. doi: 10.1016/j.mce.2018.03.018. PMID: 29673557   47. Carosa E, Lenzi A, Jannini EA. Thyroid hormone receptors and ligands, tissue distribution and sexual behavior. Mol Cell Endocrinol. 2018 May 15;467:49-59. doi: 10.1016/j.mce.2017.11.006. Epub 2017 Nov 23. PMID:  29175529   48. Ciocca G, Solano C, Di Lorenzo G, Limoncin E, Mollaioli D, Carosa E, Collazzoni A, Santarnecchi E, Bianciardi E, Niolu C, Siracusano A, Rossi A, Jannini EA. Bisexuality among a cohort of university students: prevalence and psychological distress. Int J Impot Res. 2018 Apr;30(2):79-84. doi: 10.1038/s41443-017-0014-2. Epub 2017 Dec 4. PMID: 29203843   49. Ciocca G, Limoncin E, Lingiardi V, Burri A, Jannini EA. Response Regarding Existential Issues in Sexual Medicine: The Relation Between Death Anxiety and Hypersexuality. Sex Med Rev. 2018 Apr;6(2):335-336. doi:  10.1016/j.sxmr.2018.02.002. PMID: 29605060   50. Corona G, Maggi M, Jannini EA. EDEUS, a Real-Life Study on the Users of Phosphodiesterase Type 5 Inhibitors: Prevalence, Perceptions, and Health Care-Seeking Behavior Among European Men With a Focus on 2nd-Generation Avanafil. Sex Med. 2018 Mar;6(1):15-23. doi: 10.1016/j.esxm.2017.10.003. Epub 2017 Dec 21. PMID:     29275958   51. Barbonetti A, Calogero AE, Balercia G, Garolla A, Krausz C, La Vignera S, Lombardo F, Jannini EA, Maggi M, Lenzi A, Foresta C, Ferlin A. The use of follicle stimulating hormone (FSH) for the treatment of the infertile man: position statement from the Italian Society of Andrology and Sexual Medicine (SIAMS). J Endocrinol Invest. 2018 Feb 1. doi: 10.1007/s40618-018-0843-y. [Epub ahead of print] PMID: 29392544   52. Jannini EA, Nappi RE. Couplepause: A New Paradigm in Treating Sexual Dysfunction During Menopause and Andropause. Sex Med Rev. 2018 Jan 19. pii: S2050-0521(17)30141-5. doi: 10.1016/j.sxmr.2017.11.002. [Epub ahead of print] PMID: 29371146   53. Ciocca G, Solano C, Di Lorenzo G, Limoncin E, Mollaioli D, Carosa E, Collazzoni A, Santarnecchi E, Bianciardi E, Niolu C, Siracusano A, Rossi A, Jannini EA. Bisexuality among a cohort of university students: prevalence and psychological distress. Int J Impot Res. 2017 Dec 4. doi: 10.1038/s41443-017-0014-2. [Epub ahead of print] PMID:  29203843   54. Limoncin E, D'Alfonso A, Corallino C, Cofini V, Di Febbo G, Ciocca G, Mollaioli D, Patacchiola F, Jannini EA, Carta G. The effect of voluntary termination of pregnancy on female sexual and emotional well-being in different age groups. J Psychosom Obstet Gynaecol. 2017 Dec;38(4):310-316. doi: 10.1080/0167482X.2017.1285901. Epub 2017 Feb 15. PMID: 28635530    55. Limoncin E, Gravina GL, Corona G, Maggi M, Ciocca G, Lenzi A, Jannini EA.  Erectile function recovery in men treated with phosphodiesterase type 5 inhibitor administration after bilateral nerve-sparing radical prostatectomy: a systematic review of placebo-controlled randomized trials with trial sequential analysis. Andrology. 2017 Aug 8. doi: 10.1111/andr.12403. [Epub ahead of print]   56. Gravina GL, Marampon F, Sanità P, Festuccia C, Forcella C, Scarsella L, Jitariuc A, Vetuschi A, Sferra R, Colapietro A, Carosa E, Dolci S, Lenzi A, Jannini EA. Episode-like pulse testosterone supplementation induces tumor senescence and growth arrest down-modulating androgen receptor through modulation of p-ERK1/2, pARser81 and CDK1 signaling: biological implications for men treated with testosterone replacement therapy. Oncotarget. 2017 Nov 30;8(69):113792-113806. doi: 0.18632/oncotarget.22776. eCollection 2017 Dec 26.PMID: 29371946   57. Carosa E, Lenzi A, Jannini EA. Thyroid hormone receptors and ligands, tissue distribution and sexual behavior. Mol Cell Endocrinol. 2017 Nov 23. pii: S0303-7207(17)30571-3. doi: 10.1016/j.mce.2017.11.006. [Epub ahead of print] PMID: 29175529   58. Collazzoni A, Ciocca G, Limoncin E, Marucci C, Mollaioli D, Di Sante S, Di Lorenzo G, Niolu C, Siracusano A, Maggi M, Castellini G, Rossi A, Jannini EA. Mating Strategies and Sexual Functioning in Personality Disorders: A Comprehensive Review of Literature. Sex Med Rev. 2017 Oct;5(4):414-428. doi: 10.1016/j.sxmr.2017.03.009. Epub 2017 May 16. PMID: 28526631   59. Cesarini V, Guida E, Todaro F, Di Agostino S, Tassinari V, Nicolis S, Favaro R, Caporali S, Lacal PM, Botti E, Costanzo A, Rossi P, Jannini EA, Dolci S. Sox2 is not required for melanomagenesis, melanoma growth and melanoma metastasis in vivo. Oncogene. 2017 Aug;36(31):4508-4515. doi: 10.1038/onc.2017.53. Epub 2017 Apr 3.   60. Calogero AE, Giagulli VA, Mongioì LM, Triggiani V, Radicioni AF, Jannini EA, Pasquali D; Klinefelter ItaliaN Group (KING). Klinefelter syndrome: cardiovascular abnormalities and metabolic disorders. J Endocrinol Invest. 2017 Jul;40(7):705-712. doi: 10.1007/s40618-017-0619-9. Epub 2017 Mar 3.   61. Sansone A, Sansone M, Proietti M, Ciocca G, Lenzi A, Jannini EA, Romanelli F Relationship Between Use of Videogames and Sexual Health in Adult Males. J Sex Med. 2017 Jul;14(7):898-903. doi: 10.1016/j.jsxm.2017.05.001. Epub 2017 Jun 1.   62. Jannini EA. SM = SM: The Interface of Systems Medicine and Sexual Medicine for Facing Non-Communicable Diseases in a Gender-Dependent Manner. Sex Med Rev. 2017 Jul;5(3):349-364. doi: 10.1016/j.sxmr.2017.04.002. Epub 2017 Jun 7.   63. Collazzoni A, Ciocca G, Limoncin E, Marucci C, Mollaioli D, Di Sante S, Di Lorenzo G, Niolu C, Siracusano A, Maggi M, Castellini G, Rossi A, Jannini EA. Mating Strategies and Sexual Functioning in Personality Disorders: A Comprehensive Review of Literature. Sex Med Rev. 2017 May 16. pii: S2050-0521(17)30040-9. doi: 10.1016/j.sxmr.2017.03.009. [Epub ahead of print].   64. Corona G, Pizzocaro A, Lanfranco F, Garolla A, Pelliccione F, Vignozzi L, Ferlin A, Foresta C, Jannini EA, Maggi M, Lenzi A, Pasquali D, Francavilla S; Klinefelter ItaliaN Group (KING). Sperm recovery and ICSI outcomes in Klinefelter syndrome: a systematic review and meta-analysis. Hum Reprod Update. 2017 May 1;23(3):265-275. doi: 10.1093/humupd/dmx008.   65. Kamenov Z, Fileva S, Kalinov K, Jannini EA.Evaluation of the efficacy and safety of Tribulus terrestris in male sexual dysfunction-A prospective, randomized, double-blind, placebo-controlled clinical trial. Maturitas. 2017 May;99:20-26. doi: 10.1016/j.maturitas.2017.01.011. Epub 2017 Feb 12.   66. Fisher AD, Castellini G, Ristori J, Casale H, Giovanardi G, Carone N, Fanni E, Mosconi M, Ciocca G, Jannini EA, Ricca V, Lingiardi V, Maggi M. Who has the worst attitudes toward sexual minorities? Comparison of transphobia and homophobia levels in gender dysphoric individuals, the general population and health care providers. J Endocrinol Invest. 2017 Mar;40(3):263-273. doi: 10.1007/s40618-016-0552-3. Epub 2016 Sep 17.   67. Cesarini V, Martini M, Vitiani LR, Gravina GL, Di Agostino S, Graziani G, D'Alessandris QG, Pallini R, Larocca LM, Rossi P, Jannini EA, Dolci S. Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome. Oncotarget. 2017 Feb 21;8(8):13223-13239. doi: 10.18632/oncotarget.14656.   68. Limoncin E, D'Alfonso A, Corallino C, Cofini V, Di Febbo G, Ciocca G, Mollaioli D, Patacchiola F, Jannini EA, Carta G. The effect of voluntary termination of pregnancy on female sexual and emotional well-being in different age groups. J Psychosom Obstet Gynaecol. 2017 Feb 15:1-7. doi: 10.1080/0167482X.2017.1285901. [Epub ahead of print]   69. Scaglione F, Donde S, Hassan TA, Jannini EA. Phosphodiesterase Type 5 Inhibitors for the Treatment of Erectile Dysfunction: Pharmacology and Clinical Impact of the Sildenafil Citrate Orodispersible Tablet Formulation. Clin Ther. 2017 Feb;39(2):370-377. doi: 10.1016/j.clinthera.2017.01.001. Epub 2017 Jan 28. Review.   70. Ciocca G, Niolu C, Déttore D, Antonelli P, Conte S, Tuziak B, Limoncin E, Mollaioli D, Carosa E, Gravina GL, Di Sante S, Di Lorenzo G, Fisher AD, Maggi M, Lenzi A, Siracusano A, Jannini EA. Cross-cultural and socio-demographic correlates of homophobic attitude among university students in three European countries. J Endocrinol Invest. 2017 Feb;40(2):227-233. doi: 10.1007/s40618-016-0554-1. Epub 2016 Sep 25.   71. Bonomi M, Rochira V, Pasquali D, Balercia G, Jannini EA, Ferlin A; Klinefelter ItaliaN Group (KING). Klinefelter syndrome (KS): genetics, clinical phenotype and hypogonadism. J Endocrinol Invest. 2017 Feb;40(2):123-134. doi: 10.1007/s40618-016-0541-6. Epub 2016 Sep 19.   72. Fisher WA, Gruenwald I, Jannini EA, Lev-Sagie A, Lowenstein L, Pyke RE, Reisman Y, Revicki DA, Rubio-Aurioles E. Standards for Clinical Trials in Male and Female Sexual Dysfunction: III. Unique Aspects of Clinical Trials in Male Sexual Dysfunction. J Sex Med. 2017 Jan;14(1):3-18. doi: 10.1016/j.jsxm.2016.08.016.   73. Fisher WA, Gruenwald I, Jannini EA, Lev-Sagie A, Lowenstein L, Pyke RE, Reisman Y, Revicki DA, Rubio-Aurioles E. Standards for Clinical Trials in Male and Female Sexual Dysfunction: IV. Unique Aspects of Clinical Trials in Female Sexual Dysfunction. J Sex Med. 2017 Jan;14(1):19-26. doi: 10.1016/j.jsxm.2016.09.022.   74. Fisher WA, Gruenwald I, Jannini EA, Lev-Sagie A, Lowenstein L, Pyke RE, Reisman Y, Revicki DA, Rubio-Aurioles E. Standards for Clinical Trials in Male and Female Sexual Dysfunction: II. Patient-Reported Outcome Measures. J Sex Med. 2016 Dec;13(12):1818-1827. doi: 10.1016/j.jsxm.2016.08.015.   75. Fisher WA, Gruenwald I, Jannini EA, Lev-Sagie A, Lowenstein L, Pyke RE, Reisman Y, Revicki DA, Rubio-Aurioles E. Standards for Clinical Trials in Male and Female Sexual Dysfunction: I. Phase I to Phase IV Clinical Trial Design. J Sex Med. 2016 Dec;13(12):1805-1817. doi: 10.1016/j.jsxm.2016.09.021.   76. Corona G, Rastrelli G, Burri A, Serra E, Gianfrilli D, Mannucci E, Jannini EA, Maggi M. First-generation phosphodiesterase type 5 inhibitors dropout: a comprehensive review and meta-analysis. Andrology. 2016 Nov;4(6):1002-1009. doi: 10.1111/andr.12255. Epub 2016 Sep 16.   77. Maseroli E, Fanni E, Cipriani S, Scavello I, Pampaloni F, Battaglia C, Fambrini M, Mannucci E, Jannini EA, Maggi M, Vignozzi L. Cardiometabolic Risk and Female Sexuality: Focus on Clitoral Vascular Resistance. J Sex Med. 2016 Nov;13(11):1651-1661. doi: 10.1016/j.jsxm.2016.09.009. Epub 2016 Sep 28.   78. Maseroli E, Fanni E, Mannucci E, Fambrini M, Jannini EA, Maggi M, Vignozzi L. Which are the male factors associated with female sexual dysfunction (FSD)? Andrology. 2016 Sep;4(5):911-20. doi: 10.1111/andr.12224. Epub 2016 Jul 13.   79. Limoncin E, Lotti F, Rossi M, Maseroli E, Gravina GL, Ciocca G, Mollaioli D, Di Sante S, Maggi M, Lenzi A, Jannini EA. The impact of premature ejaculation on the subjective perception of orgasmic intensity: validation and standardisation of the 'Orgasmometer'. Andrology. 2016 Sep;4(5):921-6. doi: 10.1111/andr.12220. Epub 2016 May 23.   80. Di Sante S, Mollaioli D, Gravina GL, Ciocca G, Limoncin E, Carosa E, Lenzi A, Jannini EA. Epidemiology of delayed ejaculation. Transl Androl Urol. 2016 Aug;5(4):541-8. doi: 10.21037/tau.2016.05.10.   81. McMahon CG, Jannini EA, Serefoglu EC, Hellstrom WJ. The pathophysiology of acquired premature ejaculation. Transl Androl Urol. 2016 Aug;5(4):434-49. doi: 10.21037/tau.2016.07.06.   82. Marampon F, Gravina GL, Festuccia C, Popov VM, Colapietro EA, Sanità P, Musio D, De Felice F, Lenzi A, Jannini EA, Di Cesare E, Tombolini V. Vitamin D protects endothelial cells from irradiation-induced senescence and apoptosis by modulating MAPK/SirT1 axis. J Endocrinol Invest. 2016 Apr;39(4):411-22. doi: 10.1007/s40618-015-0381-9. Epub 2015 Sep 3.   83. Corona G, Rastrelli G, Burri A, Jannini EA, Maggi M.The safety and efficacy of Avanafil, a new 2(nd) generation PDE5i: comprehensive review and meta-analysis. Expert Opin Drug Saf. 2016;15(2):237-47. doi: 10.1517/14740338.2016.1130126. Epub 2016 Jan 20. Erratum in: Expert Opin Drug Saf. 2016;15(2):v.   84. Ciocca G, Limoncin E, Carosa E, Di Sante S, Gravina GL, Mollaioli D, Gianfrilli D, Lenzi A, Jannini EA. Is Testosterone a Food for the Brain? Sex Med Rev. 2016 Jan;4(1):15-25. doi: 10.1016/j.sxmr.2015.10.007. Epub 2016 Jan 8.   85. Corona G, Rastrelli G, Limoncin E, Sforza A, Jannini EA, Maggi M. Interplay Between Premature Ejaculation and Erectile Dysfunction: A Systematic Review and Meta-Analysis. J Sex Med. 2015 Dec;12(12):2291-300. doi: 10.1111/jsm.13041. Epub 2015 Nov 9.   86. Jannini EA, Ciocca G, Limoncin E, Mollaioli D, Di Sante S, Gianfrilli D, Lombardo F, Lenzi A. Premature ejaculation: old story, new insights. Fertil Steril. 2015 Nov;104(5):1061-73. doi: 10.1016/j.fertnstert.2015.08.035. Epub 2015 Sep 26.   87. Ciocca G, Limoncin E, Mollaioli D, Gravina GL, Carosa E, Di Sante S, Gianfrilli D, Lombardo F, Lenzi A, Jannini EA. SIAMS survey on sexological screening during the assisted reproductive technologies in Italy. J Endocrinol Invest. 2015 Sep;38(9):999-1005. doi: 10.1007/s40618-015-0286-7. Epub 2015 Apr 18.     88. Ciocca G, Tuziak B, Limoncin E, Mollaioli D, Capuano N, Martini A, Carosa E, Fisher AD, Maggi M, Niolu C, Siracusano A, Lenzi A, Jannini EA. Psychoticism, Immature Defense Mechanisms and a Fearful Attachment Style are Associated with a Higher Homophobic Attitude. J Sex Med. 2015 Sep;12(9):1953-60. doi: 10.1111/jsm.12975. Epub 2015 Sep 8.   89. Gravina GL, Mancini A, Muzi P, Ventura L, Biordi L, Ricevuto E, Pompili S, Mattei C, Di Cesare E, Jannini EA, Festuccia C. CXCR4 pharmacogical inhibition reduces bone and soft tissue metastatic burden by affecting tumor growth and tumorigenic potential in prostate cancer preclinical models. Prostate. 2015 Sep;75(12):1227-46. doi: 10.1002/pros.23007. Epub 2015 Jun 12.   90. Ciocca G, Capuano N, Tuziak B, Mollaioli D, Limoncin E, Valsecchi D, Carosa E, Gravina GL, Gianfrilli D, Lenzi A, Jannini EA. Italian Validation of Homophobia Scale (HS). Sex Med. 2015 Sep;3(3):213-8. doi: 10.1002/sm2.68. Epub 2015 Apr 15.   91. Dean JD, McMahon CG, Guay AT, Morgentaler A, Althof SE, Becher EF, Bivalacqua TJ, Burnett AL, Buvat J, El Meliegy A, Hellstrom WJ, Jannini EA, Maggi M, McCullough A, Torres LO, Zitzmann M. The International Society for Sexual Medicine's Process of Care for the Assessment and Management of Testosterone Deficiency in Adult Men. J Sex Med. 2015 Aug;12(8):1660-86. doi: 10.1111/jsm.12952.   92. Ciocca G, Carosa E, Stornelli M, Limoncin E, Gravina GL, Iannarelli R, Sperandio A, Di Sante S, Lenzi A, Lauro D, Jannini EA. Post-traumatic stress disorder, coping strategies and type 2 diabetes: psychometric assessment after L'Aquila earthquake. Acta Diabetol. 2015 Jun;52(3):513-21. doi: 10.1007/s00592-014-0686-8. Epub 2014 Nov 19.   93. . Sansone A, Romanelli F, Jannini EA, Lenzi A. Hormonal correlations of premature ejaculation. Endocrine. 2015 Jun;49(2):333-8. doi: 10.1007/s12020-014-0520-7. Epub 2015 Jan 1.   94. Ciocca G, Limoncin E, Di Tommaso S, Mollaioli D, Gravina GL, Marcozzi A, Tullii A, Carosa E, Di Sante S, Gianfrilli D, Lenzi A, Jannini EA. Attachment styles and sexual dysfunctions: a case-control study of female and male sexuality. Int J Impot Res. 2015 May-Jun;27(3):81-5. doi: 10.1038/ijir.2014.33. Epub 2014 Aug 14.   95. Limoncin E, Ciocca G, Gravina GL, Carosa E, Mollaioli D, Cellerino A, Mennucci A, Di Sante S, Lenzi A, Jannini EA. Pregnant Women's Preferences for Men's Faces Differ Significantly from Nonpregnant Women. J Sex Med. 2015 May;12(5):1142-51. doi: 10.1111/jsm.12849. Epub 2015 Mar 5.   96. Jannini EA, Burri A, Jern P, Novelli G. Genetics of Human Sexual Behavior: Where We Are, Where We Are Going. Sex Med Rev. 2015 Apr;3(2):65-77. doi: 10.1002/smrj.46. Epub 2015 Dec 2.   97. Gravina GL, Di Sante S, Limoncin E, Mollaioli D, Ciocca G, Carosa E, Sanità P, Di Cesare E, Lenzi A, Jannini EA. Challenges to treat hypogonadism in prostate cancer patients: implications for endocrinologists, urologists and radiotherapists. Transl Androl Urol. 2015 Apr;4(2):139-47. doi: 10.3978/j.issn.2223-4683.2015.04.01.   98. Ciocca G, Limoncin E, Cellerino A, Fisher AD, Gravina GL, Carosa E, Mollaioli D, Valenzano DR, Mennucci A, Bandini E, Di Stasi SM, Maggi M, Lenzi A, Jannini EA. Gender identity rather than sexual orientation impacts on facial preferences. J Sex Med. 2014 Oct;11(10):2500-7. doi: 10.1111/jsm.12633. Epub 2014 Jul 27.   99. Carrell DT, Rajpert-De Meyts E, Krausz C, Jannini EA, Liu PY, Gerton GL, La Salle S, Amaral A.The need of continuous focus on improved mentoring of trainees and young investigators in the field of andrology: highlights of current programs and opportunities for the future. Andrology. 2014 Sep;2(5):649-51. doi: 10.1111/j.2047-2927.2014.00259.x.    100. Jannini EA, Buisson O, Rubio-Casillas A.Beyond the G-spot: clitourethrovaginal complex anatomy in female orgasm. Nat Rev Urol. 2014 Sep;11(9):531-8. doi: 10.1038/nrurol.2014.193. Epub 2014 Aug 12.   101. Fisher AD, Ristori J, Bandini E, Giordano S, Mosconi M, Jannini EA, Greggio NA, Godano A, Manieri C, Meriggiola C, Ricca V; Italian GnRH analogs study ONIG group, Dettore D, Maggi M. Medical treatment in gender dysphoric adolescents endorsed by SIAMS-SIE-SIEDP-ONIG. J Endocrinol Invest. 2014 Jul;37(7):675-87. doi: 10.1007/s40618-014-0077-6. Epub 2014 May 27.   102. Carosa E, Castri A, Forcella C, Sebastiani G, Di Sante S, Gravina GL, Ronchi P, Cesarini V, Dolci S, Di Stasi S, Lenzi A, Jannini EA. Platelet-derived growth factor regulation of type-5 phosphodiesterase in human and rat penile smooth muscle cells. J Sex Med. 2014 Jul;11(7):1675-84. doi: 10.1111/jsm.12568. Epub 2014 May 19.   103. Limoncin E, Galli D, Ciocca G, Gravina GL, Carosa E, Mollaioli D, Lenzi A, Jannini EA. The psychosexual profile of sexual assistants: an internet-based explorative study. PLoS One. 2014 Jun 11;9(2):e98413. doi: 10.1371/journal.pone.0098413. eCollection 2014.   104. Serefoglu EC, McMahon CG, Waldinger MD, Althof SE, Shindel A, Adaikan G, Becher EF, Dean J, Giuliano F, Hellstrom WJ, Giraldi A, Glina S, Incrocci L, Jannini E, McCabe M, Parish S, Rowland D, Segraves RT, Sharlip I, Torres LO. An evidence-based unified definition of lifelong and acquired premature ejaculation: report of the second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation. J Sex Med. 2014 Jun;11(6):1423-41. doi: 10.1111/jsm.12524. Epub 2014 May 22.   105. Althof SE, McMahon CG, Waldinger MD, Serefoglu EC, Shindel AW, Adaikan PG, Becher E, Dean J, Giuliano F, Hellstrom WJ, Giraldi A, Glina S, Incrocci L, Jannini E, McCabe M, Parish S, Rowland D, Segraves RT, Sharlip I, Torres LO. An update of the International Society of Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation (PE). J Sex Med. 2014 Jun;11(6):1392-422. doi: 10.1111/jsm.12504. Epub 2014 May 22.   106. Gravina GL, Marampon F, Sherris D, Vittorini F, Di Cesare E, Tombolini V, Lenzi A, Jannini EA, Festuccia C. Torc1/Torc2 inhibitor, Palomid 529, enhances radiation response modulating CRM1-mediated survivin function and delaying DNA repair in prostate cancer models. Prostate. 2014 Jun;74(8):852-68. doi: 10.1002/pros.22804. Epub 2014 Apr 8.   107. Althof SE, McMahon CG, Waldinger MD, Serefoglu EC, Shindel AW, Adaikan PG, Becher E, Dean J, Giuliano F, Hellstrom WJ, Giraldi A, Glina S, Incrocci L, Jannini E, McCabe M, Parish S, Rowland D, Segraves RT, Sharlip I, Torres LO. An Update of the International Society of Sexual Medicine's Guidelines for the Diagnosis and Treatment of Premature Ejaculation (PE). Sex Med. 2014 Jun;2(2):60-90. doi: 10.1002/sm2.28.   108. Serefoglu EC, McMahon CG, Waldinger MD, Althof SE, Shindel A, Adaikan G, Becher EF, Dean J, Giuliano F, Hellstrom WJ, Giraldi A, Glina S, Incrocci L, Jannini E, McCabe M, Parish S, Rowland D, Segraves RT, Sharlip I, Torres LO. An evidence-based unified definition of lifelong and acquired premature ejaculation: report of the second international society for sexual medicine ad hoc committee for the definition of premature ejaculation. Sex Med. 2014 Jun;2(2):41-59. doi: 10.1002/sm2.27. Review.   109. Limoncin E, Carta R, Gravina GL, Carosa E, Ciocca G, Di Sante S, Isidori AM, Lenzi A, Jannini EA. The sexual attraction toward disabilities: a preliminary internet-based study. Int J Impot Res. 2014 Mar-Apr;26(2):51-4. doi: 10.1038/ijir.2013.34. Epub 2013 Sep 19.   110. Fisher AD, Castellini G, Bandini E, Casale H, Fanni E, Benni L, Ferruccio N, Meriggiola MC, Manieri C, Gualerzi A, Jannini E, Oppo A, Ricca V, Maggi M, Rellini AH. Cross-sex hormonal treatment and body uneasiness in individuals with gender dysphoria. J Sex Med. 2014 Mar;11(3):709-19. doi: 10.1111/jsm.12413. Epub 2013 Dec 16.   111. Boddi V, Fisher AD, Maseroli E, Rastrelli G, Corona G, Jannini E, Ricca V, Mannucci E, Maggi M. Lack of sexual privacy affects psychological and marital domains of male sexual dysfunction. J Sex Med. 2014 Feb;11(2):431-8. doi: 10.1111/jsm.12382. Epub 2013 Nov 21.   112. Festuccia C, Mancini A, Gravina GL, Scarsella L, Llorens S, Alonso GL, Tatone C, Di Cesare E, Jannini EA, Lenzi A, D'Alessandro AM, Carmona M. Antitumor effects of saffron-derived carotenoids in prostate cancer cell models. Biomed Res Int. 2014;2014:135048. doi: 10.1155/2014/135048. Epub 2014 May 11.   113. Isidori AM, Buvat J, Corona G, Goldstein I, Jannini EA, Lenzi A, Porst H, Salonia A, Traish AM, Maggi M. A critical analysis of the role of testosterone in erectile function: from pathophysiology to treatment-a systematic review. Eur Urol. 2014 Jan;65(1):99-112. doi: 10.1016/j.eururo.2013.08.048. Epub 2013 Aug 29.   114. Isidori AM, Corona G, Aversa A, Gianfrilli D, Jannini EA, Foresta C, Maggi M, Lenzi A; SIAMS-ED Study Group. The SIAMS-ED Trial: A National, Independent, Multicentre Study on Cardiometabolic and Hormonal Impairment of Men with Erectile Dysfunction Treated with Vardenafil. Int J Endocrinol. 2014;2014:858715. doi: 10.1155/2014/858715. Epub 2014 May 15.   115. Jannini EA, Sternbach N, Limoncin E, Ciocca G, Gravina GL, Tripodi F, Petruccelli I, Keijzer S, Isherwood G, Wiedemann B, Simonelli C. Health-related characteristics and unmet needs of men with erectile dysfunction: a survey in five European countries. J Sex Med. 2014 Jan;11(1):40-50. doi: 10.1111/jsm.12344. Epub 2013 Dec 9.   116. Corona G, Rastrelli G, Monami M, Maseroli E, Jannini EA, Balercia G, Sforza A, Forti G, Mannucci E, Maggi M. Frequency of sexual activity and cardiovascular risk in subjects with erectile dysfunction: cross-sectional and longitudinal analyses. Andrology. 2013 Nov;1(6):864-71. doi: 10.1111/j.2047-2927.2013.00139.x. Epub 2013 Oct 11.   117. Buisson O, Jannini EA. Pilot echographic study of the differences in clitoral involvement following clitoral or vaginal sexual stimulation. J Sex Med. 2013 Nov;10(11):2734-40. doi: 10.1111/jsm.12279. Epub 2013 Aug 12.   118. Jannini EA, Isidori AM, Aversa A, Lenzi A, Althof SE. Which is first? The controversial issue of precedence in the treatment of male sexual dysfunctions. J Sex Med. 2013 Oct;10(10):2359-69. doi: 10.1111/jsm.12315.   119. Ciocca G, Limoncin E, Mollaioli D, Gravina GL, Di Sante S, Carosa E, Lenzi A, Jannini EA. Integrating psychotherapy and pharmacotherapy in the treatment of premature ejaculation. Arab J Urol. 2013 Sep;11(3):305-12. doi: 10.1016/j.aju.2013.04.011. Epub 2013 Sep 11.   120. Campolo F, Gori M, Favaro R, Nicolis S, Pellegrini M, Botti F, Rossi P, Jannini EA, Dolci S. Essential role of Sox2 for the establishment and maintenance of the germ cell line. Stem Cells. 2013 Jul;31(7):1408-21. doi: 10.1002/stem.1392.   121. Gravina GL, Marampon F, Muzi P, Mancini A, Piccolella M, Negri-Cesi P, Motta M, Lenzi A, Di Cesare E, Tombolini V, Jannini EA, Festuccia C. PXD101 potentiates hormonal therapy and prevents the onset of castration-resistant phenotype modulating androgen receptor, HSP90, and CRM1 in preclinical models of prostate cancer. Endocr Relat Cancer. 2013 May 21;20(3):321-37. doi: 10.1530/ERC-12-0240. Print 2013 Jun.   122. Ciocca G, Limoncin E, Di Tommaso S, Gravina GL, Di Sante S, Carosa E, Tullii A, Marcozzi A, Lenzi A, Jannini EA. Alexithymia and vaginismus: a preliminary correlation perspective. Int J Impot Res. 2013 May;25(3):113-6. doi: 10.1038/ijir.2013.5. Epub 2013 Mar 7.   123. Limoncin E, Tomassetti M, Gravina GL, Ciocca G, Carosa E, Di Sante S, Gentile V, Mirone V, Montorsi F, Lenzi A, Jannini EA. Premature ejaculation results in female sexual distress: standardization and validation of a new diagnostic tool for sexual distress. J Urol. 2013 May;189(5):1830-5. doi: 10.1016/j.juro.2012.11.007. Epub 2012 Nov 6.   124. Aversa A, Jannini EA, Maggi M, Lenzi A. Effects of testosterone replacement on response to sildenafil citrate. Ann Intern Med. 2013 Apr 2;158(7):569-70. doi: 10.7326/0003-4819-158-7-201304020-00018.    125. Corona G, Rastrelli G, Ricca V, Jannini EA, Vignozzi L, Monami M, Sforza A, Forti G, Mannucci E, Maggi M. Risk factors associated with primary and secondary reduced libido in male patients with sexual dysfunction. J Sex Med. 2013 Apr;10(4):1074-89. doi: 10.1111/jsm.12043. Epub 2013 Jan 24.   126. Fisher AD, Bandini E, Casale H, Ferruccio N, Meriggiola MC, Gualerzi A, Manieri C, Jannini E, Mannucci E, Monami M, Stomaci N, Delle Rose A, Susini T, Ricca V, Maggi M. Sociodemographic and clinical features of gender identity disorder: an Italian multicentric evaluation. J Sex Med. 2013 Feb;10(2):408-19. doi: 10.1111/j.1743-6109.2012.03006.x. Epub 2012 Nov 21.   127. Gravina GL, Festuccia C, Bonfili P, Di Staso M, Franzese P, Ruggieri V, Popov VM, Tombolini V, Masciocchi C, Carosa E, Lenzi A, Jannini EA, Di Cesare E. Strategies for imaging androgen receptor signaling pathway in prostate cancer: implications for hormonal manipulation and radiation treatment. Biomed Res Int. 2013;2013:460546. doi: 10.1155/2013/460546. Epub 2013 Oct 29. Review. Erratum in: Biomed Res Int. 2014;2014:437910. doi: 10.1155/2014/437910. Giovanni Luca, Gravina [corrected to Gravina, Giovanni L].   128. Di Siena S, Campolo F, Rossi P, Jannini EA, Dolci S, Pellegrini M. UV and genotoxic stress induce ATR relocalization in mouse spermatocytes. Int J Dev Biol. 2013;57(2-4):281-7. doi: 10.1387/ijdb.130039sd.   129. McMahon CG, Jannini E, Waldinger M, Rowland D. Standard operating procedures in the disorders of orgasm and ejaculation. J Sex Med. 2013 Jan;10(1):204-29. doi: 10.1111/j.1743-6109.2012.02824.x. Epub 2012 Sep 12.   130. Jannini EA, Limoncin E, Ciocca G, Buehler S, Krychman M. Ethical aspects of sexual medicine. Internet, vibrators, and other sex aids: toys or therapeutic instruments? J Sex Med. 2012 Dec;9(12):2994-3001. doi: 10.1111/jsm.12018.   131. Corona G, Wu FC, Forti G, Lee DM, O'Connor DB, O'Neill TW, Pendleton N, Bartfai G, Boonen S, Casanueva FF, Finn JD, Giwercman A, Han TS, Huhtaniemi IT, Kula K, Lean ME, Punab M, Vanderschueren D, Jannini EA, Mannucci E, Maggi M; EMAS Study Group.Thyroid hormones and male sexual function. Int J Androl. 2012 Oct;35(5):668-79. doi: 10.1111/j.1365-2605.2012.01266.x. Epub 2012 Jul 27.   132. Lotti F, Corona G, Rastrelli G, Forti G, Jannini EA, Maggi M. Clinical correlates of erectile dysfunction and premature ejaculation in men with couple infertility. J Sex Med. 2012 Oct;9(10):2698-707. doi: 10.1111/j.1743-6109.2012.02872.x. Epub 2012 Aug 15.   133. Corona G, Jannini EA, Vignozzi L, Rastrelli G, Maggi M. The hormonal control of ejaculation. Nat Rev Urol. 2012 Sep;9(9):508-19. doi: 10.1038/nrurol.2012.147. Epub 2012 Aug 7.   134. Corona G, Ricca V, Bandini E, Rastrelli G, Casale H, Jannini EA, Sforza A, Forti G, Mannucci E, Maggi M. SIEDY scale 3, a new instrument to detect psychological component in subjects with erectile dysfunction. J Sex Med. 2012 Aug;9(8):2017-26. doi: 10.1111/j.1743-6109.2012.02762.x. Epub 2012 May 17.   135. Jannini EA, Rubio-Casillas A, Whipple B, Buisson O, Komisaruk BR, Brody S. Female orgasm(s): one, two, several. J Sex Med. 2012 Apr;9(4):956-65. doi: 10.1111/j.1743-6109.2012.02694.x.   136. Barrios F, Filipponi D, Campolo F, Gori M, Bramucci F, Pellegrini M, Ottolenghi S, Rossi P, Jannini EA, Dolci S. SOHLH1 and SOHLH2 control Kit expression during postnatal male germ cell development. J Cell Sci. 2012 Mar 15;125(Pt 6):1455-64. doi: 10.1242/jcs.092593. Epub 2012 Feb 10.   137. Gravina GL, Marampon F, Giusti I, Carosa E, Di Sante S, Ricevuto E, Dolo V, Tombolini V, Jannini EA, Festuccia C. Differential effects of PXD101 (belinostat) on androgen-dependent and androgen-independent prostate cancer models. Int J Oncol. 2012 Mar;40(3):711-20. doi: 10.3892/ijo.2011.1270. Epub 2011 Nov 23.   138. Jannini EA, DeRogatis LR, Chung E, Brock GB. How to evaluate the efficacy of the phosphodiesterase type 5 inhibitors. J Sex Med. 2012 Jan;9(1):26-33. doi: 10.1111/j.1743-6109.2011.02611.x.   139. Gravina GL, Marampon F, Piccolella M, Motta M, Ventura L, Pomante R, Popov VM, Zani BM, Pestell RG, Tombolini V, Jannini EA, Festuccia C. Hormonal therapy promotes hormone-resistant phenotype by increasing DNMT activity and expression in prostate cancer models. Endocrinology. 2011 Dec;152(12):4550-61. doi: 10.1210/en.2011-1056. Epub 2011 Oct 11.   140. Rubio-Casillas A, Jannini EA. New insights from one case of female ejaculation. J Sex Med. 2011 Dec;8(12):3500-4. doi: 10.1111/j.1743-6109.2011.02472.x. Epub 2011 Oct 13.   141. Bandini E, Fisher AD, Ricca V, Ristori J, Meriggiola MC, Jannini EA, Manieri C, Corona G, Monami M, Fanni E, Galleni A, Forti G, Mannucci E, Maggi M. Childhood maltreatment in subjects with male-to-female gender identity disorder. Int J Impot Res. 2011 Nov-Dec;23(6):276-85. doi: 10.1038/ijir.2011.39. Epub 2011 Aug 11.   142. Jannini EA, Porst H. Case studies. A practical approach to premature ejaculation. J Sex Med. 2011 Oct;8 Suppl 4:360-7. doi: 10.1111/j.1743-6109.2011.02457.x.    143. Jannini EA, Porst H. A practical approach to premature ejaculation. Introduction: the asynchronous couple. J Sex Med. 2011 Oct;8 Suppl 4:301-3. doi: 10.1111/j.1743-6109.2011.02456.x.    144. Jannini EA, Maggi M, Lenzi A. Evaluation of premature ejaculation. J Sex Med. 2011 Oct;8 Suppl 4:328-34. doi: 10.1111/j.1743-6109.2011.02289.x. Epub 2011 May 6.   145. Giraldi A, Rellini A, Pfaus JG, Bitzer J, Laan E, Jannini EA, Fugl-Meyer AR. Questionnaires for assessment of female sexual dysfunction: a review and proposal for a standardized screener. J Sex Med. 2011 Oct;8(10):2681-706. doi: 10.1111/j.1743-6109.2011.02395.x. Epub 2011 Aug 2.   146. Gravina GL, Marampon F, Piccolella M, Biordi L, Ficorella C, Motta M, Jannini EA, Tombolini V, Festuccia C. Antitumor effects of carnertinib in castration resistant prostate cancer models: a comparative study with erlotinib. Prostate. 2011 Oct 1;71(14):1481-91. doi: 10.1002/pros.21363. Epub 2011 Mar 28.   147. Jannini EA, McMahon C, Chen J, Aversa A, Perelman M. The controversial role of phosphodiesterase type 5 inhibitors in the treatment of premature ejaculation. J Sex Med. 2011 Aug;8(8):2135-43. doi: 10.1111/j.1743-6109.2011.02401.x.   148. Gravina GL, Marampon F, Petini F, Biordi L, Sherris D, Jannini EA, Tombolini V, Festuccia C. The TORC1/TORC2 inhibitor, Palomid 529, reduces tumor growth and sensitizes to docetaxel and cisplatin in aggressive and hormone-refractory prostate cancer cells. Endocr Relat Cancer. 2011 Jul 1;18(4):385-400. doi: 10.1530/ERC-11-0045. Print 2011 Aug.   149. Jannini EA, Lenzi A. Sexual dysfunction: is acupuncture a therapeutic option for premature ejaculation? Nat Rev Urol. 2011 May;8(5):235-6. doi: 10.1038/nrurol.2011.54.    150. Jannini EA, Gravina GL, Morgentaler A, Morales A, Incrocci L, Hellstrom WJ. Is testosterone a friend or a foe of the prostate? J Sex Med. 2011 Apr;8(4):946-55. doi: 10.1111/j.1743-6109.2011.02233.x. Review. Erratum in: J Sex Med. 2011 May;8(5):1552. Mortengaler, Abraham [corrected to Morgentaler, Abraham].   151. Corona G, Jannini EA, Lotti F, Boddi V, De Vita G, Forti G, Lenzi A, Mannucci E, Maggi M. Premature and delayed ejaculation: two ends of a single continuum influenced by hormonal milieu. Int J Androl. 2011 Feb;34(1):41-8. doi: 10.1111/j.1365-2605.2010.01059.x.   152. Enquist M, Aronsson H, Ghirlanda S, Jansson L, Jannini EA. Exposure to mother's pregnancy and lactation in infancy is associated with sexual attraction to pregnancy and lactation in adulthood. J Sex Med. 2011 Jan;8(1):140-7. doi: 10.1111/j.1743-6109.2010.02065.x. Epub 2010 Oct 12.   153. Vecchio M, Navaneethan SD, Johnson DW, Lucisano G, Graziano G, Saglimbene V, Ruospo M, Querques M, Jannini EA, Strippoli GF. Interventions for treating sexual dysfunction in patients with chronic kidney disease. Cochrane Database Syst Rev. 2010 Dec 8;(12):CD007747. doi: 10.1002/14651858.CD007747.pub2.   154. Navaneethan SD, Vecchio M, Johnson DW, Saglimbene V, Graziano G, Pellegrini F, Lucisano G, Craig JC, Ruospo M, Gentile G, Manfreda VM, Querques M, Stroumza P, Torok M, Celia E, Gelfman R, Ferrari JN, Bednarek-Skublewska A, Dulawa J, Bonifati C, Hegbrant J, Wollheim C, Jannini EA, Strippoli GF.Prevalence and correlates of self-reported sexual dysfunction in CKD: a meta-analysis of observational studies. Am J Kidney Dis. 2010 Oct;56(4):670-85. doi: 10.1053/j.ajkd.2010.06.016. Review.   155. Jannini EA, Blanchard R, Camperio-Ciani A, Bancroft J. Male homosexuality: nature or culture? J Sex Med. 2010 Oct;7(10):3245-53.   156. Althof SE, Abdo CH, Dean J, Hackett G, McCabe M, McMahon CG, Rosen RC, Sadovsky R, Waldinger M, Becher E, Broderick GA, Buvat J, Goldstein I, El-Meliegy AI, Giuliano F, Hellstrom WJ, Incrocci L, Jannini EA, Park K, Parish S, Porst H, Rowland D, Segraves R, Sharlip I, Simonelli C, Tan HM; International Society for Sexual Medicine. International Society for Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation. J Sex Med. 2010 Sep;7(9):2947-69. doi: 10.1111/j.1743-6109.2010.01975.x.   157. Buisson O, Foldes P, Jannini E, Mimoun S. Coitus as revealed by ultrasound in one volunteer couple. J Sex Med. 2010 Aug;7(8):2750-4. doi: 10.1111/j.1743-6109.2010.01892.x. Epub 2010 Jul 7.   158. Gravina GL, Marampon F, Di Staso M, Bonfili P, Vitturini A, Jannini EA, Pestell RG, Tombolini V, Festuccia C. 5-Azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumors. Prostate. 2010 Aug;70(11):1166-78. doi: 10.1002/pros.21151.   159. Jannini EA, Eardley I, Sand M, Hackett G. Clinical and basic science research in sexual medicine must rely, in part, on pharmaceutical funding? J Sex Med. 2010 Jul;7(7):2331-7. doi: 10.1111/j.1743-6109.2010.01898.x.   160. Di Luigi L, Sgrò P, Fierro V, Bianchini S, Battistini G, Magini V, Jannini EA, Lenzi A. Prevalence of undiagnosed testosterone deficiency in aging athletes: does exercise training influence the symptoms of male hypogonadism? J Sex Med. 2010 Jul;7(7):2591-601. doi: 10.1111/j.1743-6109.2009.01694.x. Epub 2010 Feb 5.   161. Fisher AD, Bandini E, Ricca V, Ferruccio N, Corona G, Meriggiola MC, Jannini EA, Manieri C, Ristori J, Forti G, Mannucci E, Maggi M. Dimensional profiles of male to female gender identity disorder: an exploratory research. J Sex Med. 2010 Jul;7(7):2487-98. doi: 10.1111/j.1743-6109.2009.01687.x. Epub 2010 Jan 25.   162. . Vecchio M, Navaneethan SD, Johnson DW, Lucisano G, Graziano G, Querques M, Saglimbene V, Ruospo M, Bonifati C, Jannini EA, Strippoli GF.Treatment options for sexual dysfunction in patients with chronic kidney disease: a systematic review of randomized controlled trials. Clin J Am Soc Nephrol. 2010 Jun;5(6):985-95. doi: 10.2215/CJN.09081209. Epub 2010 May 24.   163. Jannini EA. Words of wisdom. Re: the role of short frenulum and the effects of frenulectomy on premature ejaculation. Eur Urol. 2010 Jun;57(6):1119-20. doi: 10.1016/j.eururo.2010.03.027.    164. Jannini EA, Gravina GL, Buisson O, Foldès P. A letter to the editor on the article by Burri et al. J Sex Med. 2010 Jun;7(6):2289-92; author reply 2292-4. doi: 10.1111/j.1743-6109.2010.01807.x.    165. Derogatis LR, Laan E, Brauer M, van Lunsen RH, Jannini EA, Davis SR, Fabre L, Smith LC, Basson R, Guay AT, Rubio-Aurioles E, Goldstein A, Pukall C, Kellogg S, Burrows L, Morrison P, Krychman M, Goldstein SW, Goldstein I. Responses to the proposed DSM-V changes. J Sex Med. 2010 Jun;7(6):1998-2014. doi: 10.1111/j.1743-6109.2010.01865.x.    166. Vignozzi L, Corona G, Forti G, Jannini EA, Maggi M. Clinical and therapeutic aspects of Klinefelter's syndrome: sexual function. Mol Hum Reprod. 2010 Jun;16(6):418-24. doi: 10.1093/molehr/gaq022. Epub 2010 Mar 26.   167. Meriggiola MC, Jannini EA, Lenzi A, Maggi M, Manieri C. Endocrine treatment of transsexual persons: an Endocrine Society Clinical Practice Guideline: commentary from a European perspective. Eur J Endocrinol. 2010 May;162(5):831-3. doi: 10.1530/EJE-09-1091. Epub 2010 Feb 11.   168. Jannini EA, McCabe MP, Salonia A, Montorsi F, Sachs BD. Organic vs. psychogenic? The Manichean diagnosis in sexual medicine. J Sex Med. 2010 May;7(5):1726-33. doi: 10.1111/j.1743-6109.2010.01824.x. Review.   169. Rowland D, McMahon CG, Abdo C, Chen J, Jannini E, Waldinger MD, Ahn TY. Disorders of orgasm and ejaculation in men. J Sex Med. 2010 Apr;7(4 Pt 2):1668-86. doi: 10.1111/j.1743-6109.2010.01782.x.   170. Carosa E, Di Sante S, Rossi S, Castri A, D'Adamo F, Gravina GL, Ronchi P, Kostrouch Z, Dolci S, Lenzi A, Jannini EA. Ontogenetic profile of the expression of thyroid hormone receptors in rat and human corpora cavernosa of the penis. J Sex Med. 2010 Apr;7(4 Pt 1):1381-90. doi: 10.1111/j.1743-6109.2009.01701.x. Epub 2010 Feb 5.   171. Barrios F, Filipponi D, Pellegrini M, Paronetto MP, Di Siena S, Geremia R, Rossi P, De Felici M, Jannini EA, Dolci S. Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells. J Cell Sci. 2010 Mar 15;123(Pt 6):871-80. doi: 10.1242/jcs.057968. Epub 2010 Feb 16.   172. Isidori AM, Pozza C, Esposito K, Giugliano D, Morano S, Vignozzi L, Corona G, Lenzi A, Jannini EA. Development and validation of a 6-item version of the female sexual function index (FSFI) as a diagnostic tool for female sexual dysfunction. J Sex Med. 2010 Mar;7(3):1139-46. doi: 10.1111/j.1743-6109.2009.01635.x. Epub 2009 Dec 1.   173. Jannini EA, Whipple B, Kingsberg SA, Buisson O, Foldès P, Vardi Y. Who's afraid of the G-spot? J Sex Med. 2010 Jan;7(1 Pt 1):25-34. doi: 10.1111/j.1743-6109.2009.01613.x.   174. Lombardo F, Tsamatropoulos P, Piroli E, Culasso F, Jannini EA, Dondero F, Lenzi A, Gandini L. Treatment of erectile dysfunction due to C677T mutation of the MTHFR gene with vitamin B6 and folic acid in patients non responders to PDE5i. J Sex Med. 2010 Jan;7(1 Pt 1):216-23. doi: 10.1111/j.1743-6109.2009.01463.x. Epub 2009 Aug 17.   175. Godano A, Maggi M, Jannini E, Meriggiola MC, Ghigo E, Todarello O, Lenzi A, Manieri C. SIAMS-ONIG Consensus on hormonal treatment in gender identity disorders. J Endocrinol Invest. 2009 Nov;32(10):857-64.   176. Jannini EA, Fisher WA, Bitzer J, McMahon CG.Is sex just fun? How sexual activity improves health. J Sex Med. 2009 Oct;6(10):2640-8. doi: 10.1111/j.1743-6109.2009.01477.x.   177. Jannini EA, Isidori AM, Gravina GL, Aversa A, Balercia G, Bocchio M, Boscaro M, Carani C, Corona G, Fabbri A, Foresta C, Forti G, Francavilla S, Granata AR, Maggi M, Mansani R, Palego P, Spera G, Vetri M, Lenzi A; Endotrial Study Group. The ENDOTRIAL study: a spontaneous, open-label, randomized, multicenter, crossover study on the efficacy of sildenafil, tadalafil, and vardenafil in the treatment of erectile dysfunction. J Sex Med. 2009 Sep;6(9):2547-60. doi: 10.1111/j.1743-6109.2009.01375.x. Epub 2009 Jun 29.   178. Corona G, Mannucci E, Lotti F, Boddi V, Jannini EA, Fisher AD, Monami M, Sforza A, Forti G, Maggi M. Impairment of couple relationship in male patients with sexual dysfunction is associated with overt hypogonadism. J Sex Med. 2009 Sep;6(9):2591-600. doi: 10.1111/j.1743-6109.2009.01352.x. Epub 2009 Jun 9.   179. Jannini EA, Granata AM, Hatzimouratidis K, Goldstein I. Use and abuse of Rigiscan in the diagnosis of erectile dysfunction. J Sex Med. 2009 Jul;6(7):1820-9. doi: 10.1111/j.1743-6109.2009.01343.x.   180. Foresta C, Caretta N, Corona G, Fabbri A, Francavilla S, Jannini E, Maggi M, Bettocchi C, Lenzi A. Clinical and metabolic evaluation of subjects with erectile dysfunction: a review with a proposal flowchart. Int J Androl. 2009 Jun;32(3):198-211. doi: 10.1111/j.1365-2605.2008.00932.x. Epub 2008 Dec 9.   181. Corona G, Mannucci E, Jannini EA, Lotti F, Ricca V, Monami M, Boddi V, Bandini E, Balercia G, Forti G, Maggi M. Hypoprolactinemia: a new clinical syndrome in patients with sexual dysfunction. J Sex Med. 2009 May;6(5):1457-66. doi: 10.1111/j.1743-6109.2008.01206.x. Epub 2009 Feb 10.   182. Jannini EA. Editorial comment on: Dapoxetine for the treatment of premature ejaculation: results from a randomized, double-blind, placebo-controlled phase 3 trial in 22 countries. Eur Urol. 2009 Apr;55(4):967-8. doi: 10.1016/j.eururo.2009.01.026. Epub 2009 Jan 21.    183. Abdel-Hamid IA, Jannini EA, Andersson KE.Premature ejaculation: focus on therapeutic targets. Expert Opin Ther Targets. 2009 Feb;13(2):175-93. doi: 10.1517/14728220802663549.   184. Carosa E, Rossi S, Giansante N, Gravina GL, Castri A, Dolci S, Botti F, Morelli A, Di Luigi L, Pepe M, Lenzi A, Jannini EA.The ontogenetic expression pattern of type 5 phosphodiesterase correlates with androgen receptor expression in rat corpora cavernosa. J Sex Med. 2009 Feb;6(2):388-96. doi: 10.1111/j.1743-6109.2008.01091.x. Epub 2008 Dec 9.   185. Esposito K, Ciotola M, Maiorino MI, Giugliano F, Autorino R, De Sio M, Jannini E, Lenzi A, Giugliano D. Circulating CD34+ KDR+ endothelial progenitor cells correlate with erectile function and endothelial function in overweight men. J Sex Med. 2009 Jan;6(1):107-14. doi: 10.1111/j.1743-6109.2008.01042.x.   186. Pellegrini M, Filipponi D, Gori M, Barrios F, Lolicato F, Grimaldi P, Rossi P, Jannini EA, Geremia R, Dolci S. ATRA and KL promote differentiation toward the meiotic program of male germ cells. Cell Cycle. 2008 Dec 15;7(24):3878-88. Epub 2008 Dec 26.   187. Vignozzi L, Filippi S, Morelli A, Luconi M, Jannini E, Forti G, Maggi M. Regulation of epididymal contractility during semen emission, the first part of the ejaculatory process: a role for estrogen. J Sex Med. 2008 Sep;5(9):2010-6; quiz 2017. doi: 10.1111/j.1743-6109.2008.00914.x. Review. Erratum in: J Sex Med. 2008 Oct;5(10):2480.   188. Corona G, Jannini EA, Mannucci E, Fisher AD, Lotti F, Petrone L, Balercia G, Bandini E, Chiarini V, Forti G, Maggi M. Different testosterone levels are associated with ejaculatory dysfunction. J Sex Med. 2008 Aug;5(8):1991-8. doi: 10.1111/j.1743-6109.2008.00803.x. Epub 2007 Apr 9.   189. Gravina GL, Brandetti F, Martini P, Carosa E, Di Stasi SM, Morano S, Lenzi A, Jannini EA. Measurement of the thickness of the urethrovaginal space in women with or without vaginal orgasm. J Sex Med. 2008 Mar;5(3):610-8. doi: 10.1111/j.1743-6109.2007.00739.x. Epub 2008 Jan 21.   190. Jannini EA. Editorial comment on: Relation between the Saint Louis University ADAM questionnaire and sexual hormonal levels in a male outpatient population over 50 years of age. Eur Urol. 2007 Dec;52(6):1766-7. Epub 2007 Oct 24.   191. Morano S, Mandosi E, Fallarino M, Gatti A, Tiberti C, Sensi M, Gandini L, Buchetti B, Lenti L, Jannini EA, Lenzi A. Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled study. Eur Urol. 2007 Dec;52(6):1768-74. Epub 2007 Apr 25.   192. Filipponi D, Hobbs RM, Ottolenghi S, Rossi P, Jannini EA, Pandolfi PP, Dolci S. Repression of kit expression by Plzf in germ cells. Mol Cell Biol. 2007 Oct;27(19):6770-81. Epub 2007 Jul 30.   193. Scorolli C, Ghirlanda S, Enquist M, Zattoni S, Jannini EA.Relative prevalence of different fetishes. Int J Impot Res. 2007 Jul-Aug;19(4):432-7. Epub 2007 Feb 15.   194. Millimaggi D, Mari M, D'Ascenzo S, Carosa E, Jannini EA, Zucker S, Carta G, Pavan A, Dolo V. Tumor vesicle-associated CD147 modulates the angiogenic capability of endothelial cells. Neoplasia. 2007 Apr;9(4):349-57.   195. Wylie K, Daines B, Jannini EA, Hallam-Jones R, Boul L, Wilson L, Athanasiadis L, Brewster M, Kristensen E. Loss of sexual desire in the postmenopausal woman. J Sex Med. 2007 Mar;4(2):395-405.   196. Morano S, Gatti A, Mandosi E, Tiberti C, Fallarino M, Cipriani R, Buchetti B, Gandini L, Sgrò P, Jannini EA, Lenti L, Lenzi A. Circulating monocyte oxidative activity is increased in patients with type 2 diabetes and erectile dysfunction. J Urol. 2007 Feb;177(2):655-9.   197. Balercia G, Boscaro M, Lombardo F, Carosa E, Lenzi A, Jannini EA. Sexual symptoms in endocrine diseases: psychosomatic perspectives. Psychother Psychosom. 2007;76(3):134-40.   198. Jannini EA, Lenzi A, Isidori A, Fabbri A. Subclinical erectile dysfunction: proposal for a novel taxonomic category in sexual medicine. J Sex Med. 2006 Sep;3(5):787-93; discussion 794.   199. Corona G, Jannini EA, Maggi M.Inventories for male and female sexual dysfunctions. Int J Impot Res. 2006 May-Jun;18(3):236-50.   200. Dolci S, Belmonte A, Santone R, Giorgi M, Pellegrini M, Carosa E, Piccione E, Lenzi A, Jannini EA. Subcellular localization and regulation of type-1C and type-5 phosphodiesterases. Biochem Biophys Res Commun. 2006 Mar 17;341(3):837-46. Epub 2006 Jan 23.   201. Carosa E, Lombardo F, Martini P, Brandetti F, Jannini EA.The therapeutic dilemma: how to use tadalafil. Int J Androl. 2005 Dec;28 Suppl 2:74-80.   202. Lombardo F, Gandini L, Jannini EA, Sgrò P, Gilio B, Toselli L, Dondero F, Lenzi A. Diagnosing erectile dysfunction: instruments for endocrine diagnosis. Int J Androl. 2005 Dec;28 Suppl 2:53-5.   203. Jannini EA, Lombardo F, Lenzi A. Correlation between ejaculatory and erectile dysfunction. Int J Androl. 2005 Dec;28 Suppl 2:40-5.   204. Cellerino A, Jannini EA. Why humans need type 5 phosphodiesterase inhibitors. Int J Androl. 2005 Dec;28 Suppl 2:14-7.   205. Lenzi A, Jannini EA. The andrologist from medicine of reproduction to sexual medicine: the Italian experience. Int J Androl. 2005 Dec;28 Suppl 2:9-13.   206. Carani C, Isidori AM, Granata A, Carosa E, Maggi M, Lenzi A, Jannini EA. Multicenter study on the prevalence of sexual symptoms in male hypo- and hyperthyroid patients. J Clin Endocrinol Metab. 2005 Dec;90(12):6472-9. Epub 2005 Oct 4.   207. Belmonte A, Ticconi C, Dolci S, Giorgi M, Zicari A, Lenzi A, Jannini EA, Piccione E. Regulation of phosphodiesterase 5 expression and activity in human pregnant and non-pregnant myometrial cells by human chorionic gonadotropin. J Soc Gynecol Investig. 2005 Dec;12(8):570-7.   208. Jannini EA, Lenzi A. Epidemiology of premature ejaculation. Curr Opin Urol. 2005 Nov;15(6):399-403.   209. Jannini EA, Lenzi A. Ejaculatory disorders: epidemiology and current approaches to definition, classification and subtyping. World J Urol. 2005 Jun;23(2):68-75. Epub 2005 May 18.   210. Carosa E, Radico C, Giansante N, Rossi S, D'Adamo F, Di Stasi SM, Lenzi A, Jannini EA. Ontogenetic profile and thyroid hormone regulation of type-1 and type-8 glucose transporters in rat Sertoli cells. Int J Androl. 2005 Apr;28(2):99-106.   211. Carosa E, Volpe R, Martini P, Brandetti F, Di Stasi SM, Lombardo F, Salacone P, Sgrò P, Gandini L, Lenzi A, Jannini EA. Psychosocial issues of ART in aging male. J Endocrinol Invest. 2005;28(3 Suppl):117-21.   212. Lombardo F, Sgrò P, Salacone P, Gilio B, Gandini L, Dondero F, Jannini EA, Lenzi A. Androgens and fertility. J Endocrinol Invest. 2005;28(3 Suppl):51-5.   213. Cellerino A, Jannini EA. Male reproductive physiology as a sexually selected handicap? Erectile dysfunction is correlated with general health and health prognosis and may have evolved as a marker of poor phenotypic quality. Med Hypotheses. 2005;65(1):179-84.   214. Corona G, Petrone L, Mannucci E, Jannini EA, Mansani R, Magini A, Giommi R, Forti G, Maggi M.Psycho-biological correlates of rapid ejaculation in patients attending an andrologic unit for sexual dysfunctions. Eur Urol. 2004 Nov;46(5):615-22.   215. Bultrini A, Carosa E, Colpi EM, Poccia G, Iannarelli R, Lembo D, Lenzi A, Jannini EA. Possible correlation between type 1 diabetes mellitus and female sexual dysfunction: case report and literature review. J Sex Med. 2004 Nov;1(3):337-40.   216. Lombardo F, Sgrò P, Gandini L, Dondero F, Jannini EA, Lenzi A. Might erectile dysfunction be due to the thermolabile variant of methylenetetrahydrofolate reductase? J Endocrinol Invest. 2004 Oct;27(9):883-5.   217. Carosa E, Martini P, Brandetti F, Di Stasi SM, Lombardo F, Lenzi A, Jannini EA. Type V phosphodiesterase inhibitor treatments for erectile dysfunction increase testosterone levels. Clin Endocrinol (Oxf). 2004 Sep;61(3):382-6.   218. Morelli A, Filippi S, Mancina R, Luconi M, Vignozzi L, Marini M, Orlando C, Vannelli GB, Aversa A, Natali A, Forti G, Giorgi M, Jannini EA, Ledda F, Maggi M. Androgens regulate phosphodiesterase type 5 expression and functional activity in corpora cavernosa. Endocrinology. 2004 May;145(5):2253-63. Epub 2004 Feb 5. Erratum in: Endocrinology. 2004 Jul;145(7):3152.   219. Di Stasi SM, Giannantoni A, Stephen RL, Capelli G, Giurioli A, Jannini EA, Vespasiani G. A prospective, randomized study using transdermal electromotive administration of verapamil and dexamethasone for Peyronie's disease. J Urol. 2004 Apr;171(4):1605-8.   220. Jannini EA, Lombardo F, Salacone P, Gandini L, Lenzi A. Treatment of sexual dysfunctions secondary to male infertility with sildenafil citrate. Fertil Steril. 2004 Mar;81(3):705-7.   221. Jannini EA, Lenzi A, Wagner G. New perspectives in the pharmacotherapy of erectile dysfunction. IDrugs. 2003 Dec;6(12):1165-72.   222. Crescenzi A, Graziano MF, Carosa E, Papini E, Rucci N, Nardi F, Trimboli P, Calvanese A, Jannini EA, D'Armiento M. Localization and expression of thyroid hormone receptors normal and neoplastic human thyroid. J Endocrinol Invest. 2003 Oct;26(10):1008-12.   223. Di Stasi SM, Giannantoni A, Capelli G, Jannini EA, Virgili G, Storti L, Vespasiani G. Transdermal electromotive administration of verapamil and dexamethasone for Peyronie's disease. BJU Int. 2003 Jun;91(9):825-9.   224. Jannini EA, Lenzi A. Introduction to the integrated model: medical, surgical and psychological therapies for the couple. J Endocrinol Invest. 2003;26(3 Suppl):128-31.   225. . Lombardo F, Gandini L, Santulli M, Jannini EA, Dondero F, Lenzi A.Endocrinological diagnosis in sexology. J Endocrinol Invest. 2003;26(3 Suppl):112-4.   226. D'Amati G, di Gioia CR, Proietti Pannunzi L, Pistilli D, Carosa E, Lenzi A, Jannini EA. Functional anatomy of the human vagina. J Endocrinol Invest. 2003;26(3 Suppl):92-6.   227. Lenzi A, Lombardo F, Salacone P, Gandini L, Jannini EA. Stress, sexual dysfunctions, and male infertility. J Endocrinol Invest. 2003;26(3 Suppl):72-6.   228. Pinchera A, Jannini EA, Lenzi A. Research and academic education in medical sexology. J Endocrinol Invest. 2003;26(3 Suppl):13-4.   229. Jannini EA, Simonelli C, Lenzi A.Sexological approach to ejaculatory dysfunction. Int J Androl. 2002 Dec;25(6):317-23.   230. Jannini EA, Simonelli C, Lenzi A. Disorders of ejaculation. J Endocrinol Invest. 2002 Dec;25(11):1006-19.   231. D'Amati G, di Gioia CR, Bologna M, Giordano D, Giorgi M, Dolci S, Jannini EA. Type 5 phosphodiesterase expression in the human vagina. Urology. 2002 Jul;60(1):191-5.   232. Basciani S, Mariani S, Arizzi M, Ulisse S, Rucci N, Jannini EA, Della Rocca C, Manicone A, Carani C, Spera G, Gnessi L. Expression of platelet-derived growth factor-A (PDGF-A), PDGF-B, and PDGF receptor-alpha and -beta during human testicular development and disease. J Clin Endocrinol Metab. 2002 May;87(5):2310-9.   233. Carosa E, Benvenga S, Trimarchi F, Lenzi A, Pepe M, Simonelli C, Jannini EA. Sexual inactivity results in reversible reduction of LH bioavailability. Int J Impot Res. 2002 Apr;14(2):93-9; discussion 100.   234. Screponi E, Carosa E, Di Stasi SM, Pepe M, Carruba G, Jannini EA. Prevalence of chronic prostatitis in men with premature ejaculation. Urology. 2001 Aug;58(2):198-202.   235. Canale D, Agostini M, Giorgilli G, Caglieresi C, Scartabelli G, Nardini V, Jannini EA, Martino E, Pinchera A, Macchia E. Thyroid hormone receptors in neonatal, prepubertal, and adult rat testis. J Androl. 2001 Mar-Apr;22(2):284-8.   236. Jannini EA, Crescenzi A, Rucci N, Screponi E, Carosa E, de Matteis A, Macchia E, d'Amati G, D'Armiento M. Ontogenetic pattern of thyroid hormone receptor expression in the human testis. J Clin Endocrinol Metab. 2000 Sep;85(9):3453-7.   237. Jannini EA, Screponi E, Carosa E, Pepe M, Lo Giudice F, Trimarchi F, Benvenga S. Lack of sexual activity from erectile dysfunction is associated with a reversible reduction in serum testosterone. Int J Androl. 1999 Dec;22(6):385-92.   238. Jannini EA, Carosa E, Rucci N, Screponi E, D'Armiento M.Ontogeny and regulation of variant thyroid hormone receptor isoforms in developing rat testis. J Endocrinol Invest. 1999 Dec;22(11):843-8.   239. Kostrouch Z, Kostrouchova M, Love W, Jannini E, Piatigorsky J, Rall JE. Retinoic acid X receptor in the diploblast, Tripedalia cystophora. Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13442-7.   240. Carosa E, Fanelli A, Ulisse S, Di Lauro R, Rall JE, Jannini EA. Ciona intestinalis nuclear receptor 1: a member of steroid/thyroid hormone receptor family. Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11152-7.   241. Ulisse S, Rucci N, Piersanti D, Carosa E, Graziano FM, Pavan A, Ceddia P, Arizzi M, Muzi P, Cironi L, Gnessi L, D'Armiento M, Jannini EA. Regulation by thyroid hormone of the expression of basement membrane components in rat prepubertal Sertoli cells. Endocrinology. 1998 Feb;139(2):741-7.   242. Gnessi L, Emidi A, Jannini EA, Carosa E, Maroder M, Arizzi M, Ulisse S, Spera G. Testicular development involves the spatiotemporal control of PDGFs and PDGF receptors gene expression and action. J Cell Biol. 1995 Nov;131(4):1105-21.   243. Jannini EA, Ulisse S, D'Armiento M. Thyroid hormone and male gonadal function. Endocr Rev. 1995 Aug;16(4):443-59.    244. Jannini EA, Ulisse S, D'Armiento M. Macroorchidism in juvenile hypothyroidism. J Clin Endocrinol Metab. 1995 Aug;80(8):2543-4.   245. . Ulisse S, Farina AR, Piersanti D, Tiberio A, Cappabianca L, D'Orazi G, Jannini EA, Malykh O, Stetler-Stevenson WG, D'Armiento M, Jannini EA. Follicle-stimulating hormone increases the expression of tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2 and induces TIMP-1 AP-1 site binding complex(es) in prepubertal rat Sertoli cells. Endocrinology. 1994 Dec;135(6):2479-87.   246. Jannini EA, Ulisse S, Cecconi S, Cironi L, Colonna R, D'Armiento M, Santoni A, Cifone MG. Follicle-stimulating hormone-induced phospholipase A2 activity and eicosanoid generation in rat Sertoli cells. Biol Reprod. 1994 Jul;51(1):140-5.   247. Ulisse S, Jannini EA, Carosa E, Piersanti D, Graziano FM, D'Armiento M. Inhibition of aromatase activity in rat Sertoli cells by thyroid hormone. J Endocrinol. 1994 Mar;140(3):431-6.   248. Jannini EA, Dolci S, Ulisse S, Nikodem VM. Developmental regulation of the thyroid hormone receptor alpha 1 mRNA expression in the rat testis. Mol Endocrinol. 1994 Jan;8(1):89-96.   249. Jannini EA, Ulisse S, Piersanti D, Carosa E, Muzi P, Lazar J, D'Armiento M. Early thyroid hormone treatment in rats increases testis size and germ cell number. Endocrinology. 1993 Jun;132(6):2726-8.   250. Ulisse S, Jannini EA, Pepe M, De Matteis S, D'Armiento M. Thyroid hormone stimulates glucose transport and GLUT1 mRNA in rat Sertoli cells. Mol Cell Endocrinol. 1992 Sep;87(1-3):131-7.   251. Jannini EA, Mitsuhashi T, Nikodem VM.Developmental expression of mRNAs from a rat C-erbA genomic locus. Biochem Biophys Res Commun. 1992 Apr 30;184(2):739-45.   252. Francavilla S, Cordeschi G, Properzi G, Di Cicco L, Jannini EA, Palmero S, Fugassa E, Loras B, D'Armiento M. Effect of thyroid hormone on the pre- and post-natal development of the rat testis. J Endocrinol. 1991 Apr;129(1):35-42.   253. Romano R, Jannini EA, Pepe M, Grimaldi A, Olivieri M, Spennati P, Cappa F, D'Armiento M. The effects of iodoprophylaxis on thyroid size during pregnancy. Am J Obstet Gynecol. 1991 Feb;164(2):482-5.   254. Jannini EA, Olivieri M, Francavilla S, Gulino A, Ziparo E, D'Armiento M. Ontogenesis of the nuclear 3,5,3'-triiodothyronine receptor in the rat testis. Endocrinology. 1990 May;126(5):2521-6.     255. Gnessi L, Ulisse S, Fabbri A, Jannini EA, Bonifacio V, Moretti C, Spera G, Isidori A.Isolation of a human seminal plasma peptide with bombesin-like activity. Fertil Steril. 1989 Jun;51(6):1034-9.   256. Gnessi L, Isidori A, Bolotti M, Altamura S, Ulisse S, Jannini EA, Fabbri A, Spera G. Identification of immunoreactive gastrin-releasing peptide related substances in adult rat Leydig cells. Endocrinology. 1989 Jan;124(1):558-60.   257. Fabbri A, Jannini EA, Gnessi L, Ulisse S, Moretti C, Isidori A. Neuroendocrine control of male reproductive function. The opioid system as a model of control at multiple sites. J Steroid Biochem. 1989 Jan;32(1B):145-50.   258. Fabbri A, Jannini EA, Gnessi L, Moretti C, Ulisse S, Franzese A, Lazzari R, Fraioli F, Frajese G, Isidori A. Endorphins in male impotence: evidence for naltrexone stimulation of erectile activity in patient therapy. Psychoneuroendocrinology. 1989;14(1-2):103-11.   259. Fabbri A, Jannini EA, Ulisse S, Gnessi L, Moretti C, Frajese G, Isidori A. Low serum bioactive luteinizing hormone in nonorganic male impotence: possible relationship with altered gonadotropin-releasing hormone pulsatility. J Clin Endocrinol Metab. 1988 Nov;67(5):867-75.   260. Dolci S, Manna C, Jannini EA, Piccione E, Pasetto N. ATP-content and kinetics of acrosome reaction in human spermatozoa: influence of various culture media and incubation time. Andrologia 1988 Mar-Apr;20(2):169-72.   Addresses:   University: Chair of Endocrinology & Medical Sexology (ENDOSEX) Department of Systems Medicine – University of Rome Tor Vergata Via Montpellier, 1 – 00133 Rome, Italy ph.: +39 0672596613     Mail: eajannini@gmail.com       Rome, 12.03.2021       a:0:{}" } ["meta_keywords"]=> array(1) { [0]=> string(133) "Andrologia,Endocrinologia,promuovere la salute sessuale e riproduttiva,andrology,endocrinology,further sexual and reproductive health" } ["reserved"]=> array(1) { [0]=> string(1) "0" } ["auth_ip"]=> array(1) { [0]=> string(1) "0" } } ["_fieldBoosts":protected]=> array(6) { ["content_id"]=> bool(false) ["content_title"]=> bool(false) ["description"]=> bool(false) ["meta_keywords"]=> bool(false) ["reserved"]=> bool(false) ["auth_ip"]=> bool(false) } } }