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Decreased plasma adiponectin concentration in major depression. NEUROSCIENCE LETTERS, 407(3), 211-213.";s:4:"data";s:10:"2006-10-30";s:2:"id";s:20:"PUBBLICAZIONE_111901";s:6:"handle";s:10:"2108/57116";s:9:"metadata1";s:19:"Articolo su rivista";s:9:"metadata2";N;s:9:"metadata3";s:28:"Settore MED/25 - Psichiatria";s:9:"metadata4";N;s:9:"metadata5";s:62:"Decreased plasma adiponectin concentration in major depression";s:9:"metadata6";s:111:"Leo, R; Di Lorenzo, G; Tesauro, M; Cola, C; Fortuna, E; Zanasi, M; Troisi, A; Siracusano, A; Lauro, R; Romeo, F";s:9:"metadata7";s:28:"10.1016/j.neulet.2006.08.043";s:9:"metadata8";N;s:9:"metadata9";N;s:10:"metadata10";N;}i:187;a:14:{s:9:"citazione";s:190:"Leo, R., Di Lorenzo, G., Tesauro, M., Cola, C., Fortuna, E., Zanasi, M., et al. (2006). Decreased plasma adiponectin concentration in major depression. NEUROSCIENCE LETTERS, 407(3), 211-213.";s:4:"data";s:4:"2006";s:2:"id";s:20:"PUBBLICAZIONE_240033";s:6:"handle";s:11:"2108/121164";s:9:"metadata1";s:19:"Articolo su rivista";s:9:"metadata2";s:95:"Adiponectin; Adult; Depressive Disorder, Major; Female; Humans; Male; Severity of Illness Index";s:9:"metadata3";s:33:"Settore MED/09 - Medicina Interna";s:9:"metadata4";s:832:"Adiponectin is the most abundant adipose-derived plasma protein. Recently adiponectin levels have been linked to most variables of metabolic syndrome and conventional risk factors for cardiovascular disease. However, its relation with major depression is yet unclear. We evaluated plasma adiponectin levels in 32 first-episode drug-naïve major depression (DSM-IV-TR) patients without conventional risk factors for cardiovascular disease and 32 matched healthy subjects. Major depression patients displayed lower adiponectin plasma levels compared to controls (P<0.01). Adiponectin significantly correlated with depression severity, as assessed by HAM-D (rho=0.83, P<0.001). This study shows decreased plasma adiponectin concentrations in major depression patients and relates adiponectinemia reduction to major depression severity.";s:9:"metadata5";s:62:"Decreased plasma adiponectin concentration in major depression";s:9:"metadata6";s:111:"Leo, R; Di Lorenzo, G; Tesauro, M; Cola, C; Fortuna, E; Zanasi, M; Troisi, A; Siracusano, A; Lauro, R; Romeo, F";s:9:"metadata7";s:28:"10.1016/j.neulet.2006.08.043";s:9:"metadata8";N;s:9:"metadata9";N;s:10:"metadata10";N;}i:188;a:14:{s:9:"citazione";s:92:"Siracusano, A., & Rubino, I.A. (2006). Psicoterapia e neuroscienze. 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HEADACHE, 45(5), 561-570.";s:4:"data";s:7:"2005-05";s:2:"id";s:20:"PUBBLICAZIONE_161515";s:6:"handle";s:11:"2108/101509";s:9:"metadata1";s:19:"Articolo su rivista";s:9:"metadata2";N;s:9:"metadata3";s:27:"Settore MED/26 - Neurologia";s:9:"metadata4";N;s:9:"metadata5";s:143:"Depressive symptoms and insecure attachment as predictors of disability in a clinical population of patients with episodic and chronic migraine";s:9:"metadata6";s:101:"Rossi, P; Di Lorenzo, G; Malpezzi, M; Di Lorenzo, C; Cesarino, F; Faroni, J; Siracusano, A; Troisi, A";s:9:"metadata7";s:32:"10.1111/j.1526-4610.2005.05110.x";s:9:"metadata8";N;s:9:"metadata9";N;s:10:"metadata10";N;}i:192;a:14:{s:9:"citazione";s:280:"Centonze, D., Palmieri, M., Boffa, L., Pierantozzi, M., Stanzione, P., Brusa, L., et al. (2005). Cortical hyperexcitability in post-traumatic stress disorder secondary to minor accidental head trauma: a neurophysiologic study. 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In women with eating disorders, but not in healthy control women, plasma ghrelin concentrations were negatively correlated with body mass index (BMI) and plasma concentrations of thyreotropin (TSH), free T3 and free T4, and positively correlated with plasma concentrations of cortisol. The ghrelin concentrations of women with binge-eating and purging behavior were significantly lower than those of women with anorexia nervosa, restricting type, and there was a negative relation between the frequency and severity of binge-eating and purging behavior, as measured by the BULIT-R total score, and ghrelin concentrations. In a multivariate regression model controlling for the confounding effects of body mass index (BMI) and age, higher ghrelin concentrations were correlated with lower BULIT-R total scores. The results of this study did not confirm the hypothesis advanced in previous studies that ghrelin concentrations are higher in patients with binge-eating/purging forms of eating disorders. 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