Alessandro Desideri

Fonte dei dati: Archivio della Ricerca
  1. Laudisi, F., Stolfi, C., Bevivino, G., Maresca, C., Franze, E., Troncone, E., et al. (2022). GATA6 Deficiency Leads to Epithelial Barrier Dysfunction and Enhances Susceptibility to Gut Inflammation. JOURNAL OF CROHN'S AND COLITIS (ONLINE), 16(2), 301-311 [10.1093/ecco-jcc/jjab145]. Dettagli
  2. Teofani, A., Marafini, I., Laudisi, F., Pietrucci, D., Salvatori, S., Unida, V., et al. (2022). Intestinal Taxa Abundance and Diversity in Inflammatory Bowel Disease Patients: An Analysis including Covariates and Confounders. NUTRIENTS, 14(2) [10.3390/nu14020260]. Dettagli
  3. Raniolo, S., Unida, V., Vindigni, G., Stolfi, C., Iacovelli, F., Desideri, A., et al. (2021). Combined and selective miR-21 silencing and doxorubicin delivery in cancer cells using tailored DNA nanostructures. CELL DEATH & DISEASE, 12(1) [10.1038/s41419-020-03339-3]. Dettagli
  4. Romeo, A., Falconi, M., Desideri, A., & Iacovelli, F. (2021). Reconstructing the Free Energy Profiles Describing the Switching Mechanism of a pH-Dependent DNA Nanodevice from ABMD Simulations. APPLIED SCIENCES, 11(9), 4052 [10.3390/app11094052]. Dettagli
  5. Vindigni, G., Raniolo, S., Iacovelli, F., Unida, V., Stolfi, C., Desideri, A., et al. (2021). Aptamer linked to DNA nanostructures diverts its traffic inside cancer cells and improves its therapeutic efficacy. PHARMACEUTICS, 13(10). Dettagli
  6. Raniolo, S., Iacovelli, F., Unida, V., Desideri, A., & Biocca, S. (2020). In Silico and In Cell Analysis of Openable DNA Nanocages for miRNA Silencing. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(1), 61 [10.3390/ijms21010061]. Dettagli
  7. Lopes, B., da Costa, M.f., de Genova Ribeiro, A., Lima, C.s., Caruso, I.p., de Araujo, G.c., et al. (2020). Quercetin pentaacetate inhibits in vitro human respiratory syncytial virus adhesion. VIRUS RESEARCH, 276, 197805 [10.1016/j.virusres.2019.197805]. Dettagli
  8. Pietrucci, D., Teofani, A., Unida, V., Cerroni, R., Biocca, S., Stefani, A., et al. (2020). Can gut microbiota be a good predictor for Parkinson's disease? A machine learning approach. BRAIN SCIENCES, 10(4) [10.3390/brainsci10040242]. Dettagli
  9. Lai, S., Molfino, A., Testorio, M., Perrotta, A.m., Currado, A., Pintus, G., et al. (2019). Effect of low-protein diet and inulin on microbiota and clinical parameters in patients with chronic kidney disease. NUTRIENTS, 11(12), 3006 [10.3390/nu11123006]. Dettagli
  10. Arrabito, G., Ferrara, V., Ottaviani, A., Cavaleri, F., Cubisino, S., Cancemi, P., et al. (2019). Imbibition of Femtoliter-Scale DNA-Rich Aqueous Droplets into Porous Nylon Substrates by Molecular Printing. LANGMUIR, 35(52), 17156-17165. Dettagli
  11. Oliveira, C.G., Romero-Canelon, I., Silva, M.M., Coverdale, J., Maia, P., Batista, A.A., et al. (2019). Palladium(ii) complexes with thiosemicarbazones derived from pyrene as topoisomerase IB inhibitors. DALTON TRANSACTIONS, 48(44), 16509-16517. Dettagli
  12. Da Silva, M.M., De Camargo, M.S., Correa, R.S., Castelli, S., De Grandis, R.A., Takarada, J.E., et al. (2019). Non-mutagenic Ru(ii) complexes: Cytotoxicity, topoisomerase IB inhibition, DNA and HSA binding. DALTON TRANSACTIONS, 48(39), 14885-14897. Dettagli
  13. Raniolo, S., Croce, S., Thomsen, R.P., Okholm, A.H., Unida, V., Iacovelli, F., et al. (2019). Cellular uptake of covalent and non-covalent DNA nanostructures with different sizes and geometries. NANOSCALE, 11(22), 10808-10818. Dettagli
  14. Iacovelli, F., Cabungcal Hernandez, K., Desideri, A., & Falconi, M. (2019). Probing the Functional Topology of a pH-Dependent Triple Helix DNA Nanoswitch Family through Gaussian Accelerated MD Simulation. JOURNAL OF CHEMICAL INFORMATION AND MODELING, 59(6), 2746-2752 [10.1021/acs.jcim.9b00133]. Dettagli
  15. Pietrucci, D., Cerroni, R., Unida, V., Farcomeni, A., Pierantozzi, M., Mercuri, N.b., et al. (2019). Dysbiosis of gut microbiota in a selected population of Parkinson's patients. PARKINSONISM & RELATED DISORDERS, 1-7 [10.1016/j.parkreldis.2019.06.003]. Dettagli
  16. Ottaviani, A., Iacovelli, F., Idili, A., Falconi, M., Ricci, F., & Desideri, A. (2018). Engineering a responsive DNA triple helix into an octahedral DNA nanostructure for a reversible opening/closing switching mechanism: a computational and experimental integrated study. NUCLEIC ACIDS RESEARCH, 46(19), 9951-9959 [10.1093/nar/gky857]. Dettagli
  17. Raniolo, S., Vindigni, G., Unida, V., Ottaviani, A., Romano, E., Desideri, A., et al. (2018). Entry, fate and degradation of DNA nanocages in mammalian cells: a matter of receptors. NANOSCALE, 10(25), 12078-12086 [10.1039/c8nr02411a]. Dettagli
  18. Wang, Z., Ouyang, H., Tesauro, C., Ottaviani, A., He, Y., Fiorani, P., et al. (2018). Real-time analysis of cleavage and religation activity of human topoisomerase 1 based on ternary fluorescence resonance energy transfer DNA substrate. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 643, 1-6. Dettagli
  19. Cardamone, F., Falconi, M., & Desideri, A. (2018). Molecular dynamics characterization of the SAMHD1 Aicardi–Goutières Arg145Gln mutant: structural determinants for the impaired tetramerization. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 32(5), 623-632. Dettagli
  20. Errico, V., Arrabito, G., Fornetti, E., Fuoco, C., Testa, S., Saggio, G., et al. (2018). High-Density ZnO Nanowires as a Reversible Myogenic-Differentiation Switch. ACS APPLIED MATERIALS & INTERFACES, 10(16), 14097-14107. Dettagli
  21. Mastrorilli, E., Pietrucci, D., Barco, L., Ammendola, S., Petrin, S., Longo, A., et al. (2018). A comparative genomic analysis provides novel insights into the ecological success of the monophasic Salmonella serovar 4,[5],12:i:-. FRONTIERS IN MICROBIOLOGY, 9(APR) [10.3389/fmicb.2018.00715]. Dettagli
  22. Raniolo, S., Vindigni, G., Ottaviani, A., Unida, V., Iacovelli, F., Manetto, A., et al. (2018). Selective targeting and degradation of doxorubicin-loaded folate-functionalized DNA nanocages. NANOMEDICINE, 14(4), 1181-1190 [10.1016/j.nano.2018.02.002]. Dettagli
  23. Takarada, J.e., Guedes, A., Correa, R.s., Silveira-Lacerda, E., Castelli, S., Iacovelli, F., et al. (2017). Ru/Fe bimetallic complexes: Synthesis, characterization, cytotoxicity and study of their interactions with DNA/HSA and human topoisomerase IB. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 636, 28-41 [10.1016/]. Dettagli
  24. Velásquez, A., Ribeiro, W., Venn, V., Castelli, S., Santoro, M., de Assis, R., et al. (2017). Efficacy of a Binuclear Cyclopalladated Compound Therapy for cutaneous leishmaniasis in the murine model of infection with Leishmania amazonensis and its inhibitory effect on Topoisomerase 1B. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61(8), AAC.00688-17. Dettagli
  25. Iacovelli, F., Idili, A., Benincasa, A., Mariottini, D., Ottaviani, A., Falconi, M., et al. (2017). Simulative and experimental characterization of a pH-dependent clamp-like DNA triple-helix nanoswitch. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139(15), 5321-5329 [10.1021/jacs.6b11470]. Dettagli
  26. Cardamone, F., Iacovelli, F., Chillemi, G., Falconi, M., & Desideri, A. (2017). A molecular dynamics simulation study decodes the early stage of the disassembly process abolishing the human SAMHD1 function. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 31(5), 497-505 [10.1007/s10822-017-0014-9]. Dettagli
  27. Cardamone, F., Pizzi, S., Iacovelli, F., Falconi, M., & Desideri, A. (2017). Virtual Screening for the Development of Dual-Inhibitors Targeting Topoisomerase IB and Tyrosyl-DNA Phosphodiesterase 1. CURRENT DRUG TARGETS, 18, 544-555 [10.2174/1389450116666150727114742]. Dettagli
  28. Chillemi, G., Kehrloesser, S., Bernassola, F., Desideri, A., Dotsch, V., Levine, A., et al. (2017). Structural evolution and dynamics of the p53 proteins. COLD SPRING HARBOR PERSPECTIVES IN MEDICINE, 7(4), a028308. Dettagli
  29. De Grandis, R.A., de Camargo, M.S., da Silva, M.M., Lopes, E.O., Padilha, E.C., Resende, F.A., et al. (2017). Human topoisomerase inhibition and DNA/BSA binding of Ru(II)–SCAR complexes as potential anticancer candidates for oral application. BIOMETALS, 30(3), 321-334 [10.1007/s10534-017-0008-z]. Dettagli
  30. Franch, O., Iacovelli, F., Falconi, M., Juul, S., Ottaviani, A., Benvenuti, C., et al. (2016). DNA hairpins promote temperature controlled cargo encapsulation in a truncated octahedral nanocage structure family. NANOSCALE, 8(27), 13333-13341 [10.1039/c6nr01806h]. Dettagli
  31. Morozzo della Rocca, B., Coletta, A., Iacovelli, F., & Desideri, A. (2016). Investigating the opening mechanism of topoisomerase I B in complex with DNA by means of metadynamics. Paper presented at Bioinformatics Italian Society Meeting 2016. Dettagli
  32. Vindigni, G., Raniolo, S., Ottaviani, A., Falconi, M., Franch, O., Knudsen, B.r., et al. (2016). Receptor-Mediated Entry of Pristine Octahedral DNA Nanocages in Mammalian Cells. ACS NANO [10.1021/acsnano.6b01402]. Dettagli
  33. Alves, C., Iacovelli, F., Falconi, M., Cardamone, F., Morozzo Della Rocca, B., de Oliveira, C., et al. (2016). A Simple and Fast Semiautomatic Procedure for the Atomistic Modeling of Complex DNA Polyhedra. JOURNAL OF CHEMICAL INFORMATION AND MODELING, 56(5), 941-949 [10.1021/acs.jcim.5b00586]. Dettagli
  34. Samia, L., Parrilha, G.l., Da Silva, J.g., Ramos, J.p., Souza-Fagundes, E.m., Castelli, S., et al. (2016). Metal complexes of 3-(4-bromophenyl)-1-pyridin-2-ylprop-2-en-1-one thiosemicarbazone: cytotoxic activity and investigation on the mode of action of the gold(III) complex. BIOMETALS, 29(3), 515-526 [10.1007/s10534-016-9933-5]. Dettagli
  35. Cicero, D.O., Di Marino, S., Dinallo, V., Pero, M., Summa, V., Desideri, A., et al. (2016). A Small Sided Game session effects salivary metabolic levels in young soccer players. BIOMEDICAL SPECTROSCOPY AND IMAGING. Dettagli
  36. D'Abramo, M., Besker, N., Desideri, A., Levine, A., Melino, G., & Chillemi, G. (2016). The p53 tetramer shows an induced-fit interaction of the C-terminal domain with the DNA-binding domain. ONCOGENE, 35(25), 3272-3281. Dettagli
  37. Errico, V., Molinaro, R., Gargioli, C., Ferranti, F., Dinescu, M., Cannata, S., et al. (2016). Cells microenvironment engineering multiphoton absorption for muscle regeneration optimization. Paper presented at 9th International Conference on Biomedical Electronics and Devices, BIODEVICES 2016 - Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016, ita. Dettagli
  38. Iacovelli, F., Falconi, M., Knudsen, B.r., & Desideri, A. (2016). Comparative simulative analysis of single and double stranded truncated octahedral DNA nanocages. RSC ADVANCES, 6(42), 35160-35166 [10.1039/c5ra27591a]. Dettagli
  39. Vutey, V., Castelli, S., D'Annessa, I., Samia, L., Souza-Fagundes, E.m., Beraldo, H., et al. (2016). Human topoisomerase IB is a target of a thiosemicarbazone copper(II) complex. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 606, 34-40 [10.1016/]. Dettagli
  40. de Camargo, M., da Silva, M., Correa, R., Vieira, S., Castelli, S., D'Anessa, I., et al. (2016). Inhibition of human DNA topoisomerase IB by nonmutagenic ruthenium(ii)-based compounds with antitumoral activity. METALLOMICS, 8(2), 179-192 [10.1039/C5MT00227C]. Dettagli
  41. Vieira, S., Castelli, S., & Desideri, A. (2015). Importance of a stable topoisomerase IB clamping for an efficient DNA processing: Effect of the Lys369Glu mutation. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 81, 76-82 [10.1016/j.ijbiomac.2015.07.044]. Dettagli
  42. Biocca, S., & Desideri, A. (2015). The Potential of Nucleic Acid-Based Nanoparticles for Biomedical Application. NANO LIFE, 5(4), 1541004. Dettagli
  43. Biocca, S., Iacovelli, F., Matarazzo, S., Vindigni, G., Oteri, F., Desideri, A., et al. (2015). Molecular mechanism of statin-mediated LOX-1 inhibition. CELL CYCLE, 14(10), 1583-1595 [10.1080/15384101.2015.1026486]. Dettagli
  44. Capobianchi, M., Gruber, C., Carletti, F., Meschi, S., Castilletti, C., Vairo, F., et al. (2015). Molecular signature of the Ebola virus associated with the fishermen community outbreak in Aberdeen, Sierra Leone, in February 2015. GENOME ANNOUNCEMENTS, 3(5), e01093-15 [10.1128/genomeA.01093-15]. Dettagli
  45. Castilletti, C., Carletti, F., Gruber, C., Bordi, L., Lalle, E., Quartu, S., et al. (2015). Molecular characterization of the first Ebola virus isolated in Italy, from a health care worker repatriated from Sierra Leone. GENOME ANNOUNCEMENTS, 3(3), e00639-15 [10.1128/genomeA.00639-15]. Dettagli
  46. D'Annessa, I., Castelli, S., & Desideri, A. (2015). Topoisomerase 1B as a target against Leishmaniasis. MINI-REVIEWS IN MEDICINAL CHEMISTRY, 15(3), 203-210. Dettagli
  47. Jahan, Z., Cerreto, M., Aversa, G., Rufini, S., Desideri, A., & Giovanetti, A. (2015). Role of topoisomerase IB on damage induced by ionizing radiation. In K P Mishra Editor (a cura di), Biological Responses, Monitoring and Protection from Radiation Exposure (pp. 193-206). Hauppauge NY 11788-3619 : Nova Science Publishers, Inc.. Dettagli
  48. Leon, I., Cadavid Vargas, J., Tiscornia, I., Porro, V., Castelli, S., Katkar, P., et al. (2015). Oxidovanadium(IV) complexes with chrysin and silibinin: Anticancer activity and mechanisms of action in a human colon adenocarcinoma model. JBIC, 20(7), 1175-1191. Dettagli
  49. Molinaro, R., Rufini S, Saggio, G., Errico, V., Ferranti, F., & Desideri, A. (2015). Role of electro-mechanical stress on the switch proliferation/differentiation on C2C12 cells. In Proceedings of Biophysics@Rome 2015. Dettagli
  50. Vieira, S., Castelli, S., Falconi, M., Takarada, J., Fiorillo, G., Buzzetti, F., et al. (2015). Role of 13-(di)phenylalkyl berberine derivatives in the modulation of the activity of human topoisomerase IB. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 77, 68-75 [10.1016/j.ijbiomac.2015.02.051]. Dettagli
  51. Wang, Z., D'Annessa, I., Tesauro, C., Croce, S., Ottaviani, A., Fiorani, P., et al. (2015). Mutation of Gly717Phe in human topoisomerase 1B has an effect on enzymatic function, reactivity to the camptothecin anticancer drug and on the linker domain orientation. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 1854(8), 860-868 [10.1016/j.bbapap.2015.04.017]. Dettagli
  52. Zuccaro, L., Krieg, J., Desideri, A., Kern, K., & Balasubramanian, K. (2015). Tuning the isoelectric point of graphene by electrochemical functionalization. SCIENTIFIC REPORTS, 5(1), 11794. Dettagli


    Zuccaro, L., Krieg, J., Desideri, A., Kern, K., & Balasubramanian, K. (2015). Tuning the isoelectric point of graphene by electrochemical functionalization. SCIENTIFIC REPORTS, 5(1), 11794.
    Articolo su rivista
    Settore BIO/11
    Tutti gli Autori
    Tuning the isoelectric point of graphene by electrochemical functionalization
    Zuccaro, L; Krieg, J; Desideri, A; Kern, K; Balasubramanian, K
  53. Zuccaro, L., Tesauro, C., Kurkina, T., Fiorani, P., Yu, H., Knudsen, B., et al. (2015). Real-Time Label-Free Direct Electronic Monitoring of Topoisomerase Enzyme Binding Kinetics on Graphene. ACS NANO, 9(11), 11166-11176 [10.1021/acsnano.5b05709]. Dettagli
  54. Biagini, T., Bartolini, B., Giombini, E., Capobianchi, M.r., Ferre, F., Chillemi, G., et al. (2014). Performances of bioinformatics pipelines for the identification of pathogens in clinical samples with the de novo assembly approaches: Focus on 2009 pandemic influenza A (H1N1). THE OPEN BIOINFORMATICS JOURNAL, 8(1), 1-5 [10.2174/1875036201408010001]. Dettagli
  55. Chandramouli, B., Chillemi, G., & Desideri, A. (2014). Structural dynamics of V3 loop in a trimeric ambiance, a molecular dynamics study on gp120-CD4 trimeric mimic. JOURNAL OF STRUCTURAL BIOLOGY, 186(1), 132-140 [10.1016/j.jsb.2014.02.014]. Dettagli
  56. D'Annessa, I., Coletta, A., & Desideri, A. (2014). Geometrical constraints limiting the poly(ADP-ribose) conformation investigated by molecular dynamics simulation. BIOPOLYMERS, 101, 78-86. Dettagli
  57. D'Annessa, I., Coletta, A., Sutthibutpong, T., Mitchell, J., Chillemi, G., Harris, S., et al. (2014). Simulations of DNA topoisomerase 1B bound to supercoiled DNA reveal changes in the flexibility pattern of the enzyme and a secondary protein-DNA binding site. NUCLEIC ACIDS RESEARCH [10.1093/nar/gku654]. Dettagli
  58. Iacovelli, F., Alves, C., Falconi, M., Oteri, F., de Oliveira, C., & Desideri, A. (2014). Influence of the single-strand linker composition on the structural/dynamical properties of a truncated octahedral DNA nano-cage family. BIOPOLYMERS, 101(10), 992-999 [10.1002/bip.22475]. Dettagli
  59. Katkar, P., Coletta, A., Castelli, S., Sabino, G.L., Couto, R.A., Ferreira, A.M., et al. (2014). Effect of oxindolimine copper(II) and zinc(II) complexes on human topoisomerase I activity. METALLOMICS, 6(1), 117-125. Dettagli
  60. Saggio, G., Bianchi, L., Castelli, S., Santucci, M.B., Fraziano, M., & Desideri, A. (2014). In vitro analysis of pyrogenicity and cytotoxicity profiles of flex sensors to be used to sense human joint postures. SENSORS, 14(7), 11672-11681 [10.3390/s140711672]. Dettagli
  61. Tesauro, C., Graziani, G., Arnò, B., Zuccaro, L., Muzi, A., D'Annessa, I., et al. (2014). Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 33(1), 71 [10.1186/s13046-014-0071-z]. Dettagli
  62. Zuccaro, L., Tesauro, C., Cerroni, B., Ottaviani, A., Knudsen, B.R., Balasubramanian, K., et al. (2014). Rolling circle amplification-based detection of human topoisomerase I activity on magnetic beads. ANALYTICAL BIOCHEMISTRY, 451, 42-44. Dettagli
  63. Biocca, S., Arcangeli, T., Tagliaferri, E., Testa, B., Vindigni, G., Oteri, F., et al. (2013). Simulative and experimental investigation on the cleavage site that generates the soluble human LOX-1. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 540(1-2), 9-18 [10.1016/]. Dettagli
  64. Juul, S., Iacovelli, F., Falconi, M., Kragh, S., Christensen, B., Frøhlich, R., et al. (2013). Temperature-controlled encapsulation and release of an active enzyme in the cavity of a self-assembled DNA nanocage. ACS NANO, 7(11), 9724-9734 [10.1021/nn4030543]. Dettagli
  65. Jensen, P., Falconi, M., Kristoffersen, E., Simonsen, A., Cifuentes, J., Marcussen, L., et al. (2013). Real-time detection of TDP1 activity using a fluorophore-quencher coupled DNA-biosensor. BIOSENSORS & BIOELECTRONICS, 48, 230-237 [10.1016/j.bios.2013.04.019]. Dettagli
  66. Tesauro, C., Morozzo Della Rocca, B., Ottaviani, A., Coletta, A., Zuccaro, L., Arnò, B., et al. (2013). Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico. MOLECULAR CANCER, 12(1), 100-100 [10.1186/1476-4598-12-100]. Dettagli
  67. Falconi, M., Iacovelli, F., & Desideri, A. (2013). A structural modeling approach for the understanding of initiation and elongation of ALS-linked superoxide dismutase fibrils. JOURNAL OF MOLECULAR MODELING, 19(9), 3695-3704 [10.1007/s00894-013-1896-7]. Dettagli
  68. Falconi, M., Ciccone, S., D'Arrigo, P., Viani, F., Sorge, R., Novelli, G., et al. (2013). Design of a novel LOX-1 receptor antagonist mimicking the natural substrate. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 438(2), 340-345 [10.1016/j.bbrc.2013.07.073]. Dettagli
  69. Castelli, S., Katkar, P., Vassallo, O., Falconi, M., Linder, S., & Desideri, A. (2013). A natural anticancer agent thaspine targets human topoisomerase IB. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 13(2), 356-363 [10.2174/1871520611313020021]. Dettagli
  70. Castelli, S., Stella, L., Petrarca, P., Battistoni, A., Desideri, A., & Falconi, M. (2013). Zinc ion coordination as a modulating factor of the ZnuA histidine-rich loop flexibility: a molecular modeling and fluorescence spectroscopy study. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 430(2), 769-773 [10.1016/j.bbrc.2012.11.073]. Dettagli
  71. Arnò, B., Coletta, A., Tesauro, C., Zuccaro, L., Fiorani, P., Lentini, S., et al. (2013). A small organic compound enhances the religation reaction of human topoisomerase I and identifies crucial elements for the religation mechanism. BIOSCIENCE REPORTS, 33(2), 269 [10.1042/BSR20120118]. Dettagli
  72. Arnò, B., D'Annessa, I., Tesauro, C., Zuccaro, L., Ottaviani, A., Knudsen, B., et al. (2013). Replacement of the human topoisomerase linker domain with the plasmodial counterpart renders the enzyme camptothecin resistant. PLOS ONE. Dettagli
  73. Chillemi, G., Davidovich, P., D'Abramo, M., Mametnabiev, T., Garabadzhiu, A.V., Desideri, A., et al. (2013). Molecular dynamics of the full-length p53 monomer. CELL CYCLE, 12(18), 3098-3108 [10.4161/cc.26162]. Dettagli
  74. Coletta, A., & Desideri, A. (2013). Role of the protein in the DNA sequence specificity of the cleavage site stabilized by the camptothecin topoisomerase IB inhibitor: a metadynamics study. NUCLEIC ACIDS RESEARCH, 41(22), 9977-9986 [10.1093/nar/gkt790]. Dettagli
  75. Coletta, A., Castelli, S., Chillemi, G., Sanna, N., Cushman, M., Pommier, Y., et al. (2013). Solvent dependency of the UV-Vis spectrum of indenoisoquinolines: role of keto-oxygens as polarity interaction probes. PLOS ONE. Dettagli
  76. D'Annessa, I., Tesauro, C., Wang, Z., Arnò, B., Zuccaro, L., Fiorani, P., et al. (2013). The human topoisomerase 1B Arg634Ala mutation results in camptothecin resistance and loss of inter-domain motion correlation. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 1834(12), 2712-2721. Dettagli
  77. Jahan, Z., Castelli, S., Aversa, G., Rufini, S., Desideri, A., & Giovanetti, A. (2013). Role of human topoisomerase IB on ionizing radiation induced damage. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 432(3), 545-548 [10.1016/j.bbrc.2013.02.032]. Dettagli
  78. Prada, C.F., Alvarez-Velilla, R., Balaña-Fouce, R., Prieto, C., Calvo-Alvarez, E., Escudero-Martínez, J.M., et al. (2013). Gimatecan and other camptothecin derivatives poison Leishmania DNA-topoisomerase IB leading to a strong leishmanicidal effect. BIOCHEMICAL PHARMACOLOGY, 85, 1433-1440. Dettagli
  79. Juul, S., Nielsen, C.J., Labouriau, R., Roy, A., Tesauro, C., Jensen, P.W., et al. (2012). Droplet microfluidics platform for highly sensitive and quantitative detection of malaria-causing Plasmodium parasites based on enzyme activity measurement. ACS NANO, 6(12), 10676-10683 [10.1021/nn3038594]. Dettagli
  80. Castelli, S., Coletta, A., D'Annessa, I., Fiorani, P., Tesauro, C., & Desideri, A. (2012). Interaction between natural compounds and human topoisomerase I. BIOLOGICAL CHEMISTRY, 393(11), 1327-1340. Dettagli
  81. Chandramouli, B., Chillemi, G., Abbate, I., Capobianchi, M., Rozera, G., & Desideri, A. (2012). Importance of V3 loop flexibility and net charge in the context of co-receptor recognition. A molecular dynamics study on HIV gp120. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 29(5), 879-891. Dettagli
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  92. Oteri, F., Falconi, M., Chillemi, G., Andersen, F.F., Oliveira, C., Pedersen, J.P., et al. (2011). Simulative Analysis of a Truncated Octahedral DNA Nanocage Family Indicates the Single-Stranded Thymidine Linkers as the Major Player for the Conformational Variability. JOURNAL OF PHYSICAL CHEMISTRY. C, 115(34), 16819-16827 [10.1021/jp203999x]. Dettagli
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  95. Balasubramanian, C., Prasad Ojha, R., Maiti, S., & Desideri, A. (2010). Sampling the structure of the noncanonical lin-4:lin-14 microRNA:mRNA complex by molecular dynamics simulations. JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL, 114, 16443-16449. Dettagli
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  99. Morozzo della Rocca, B., Smith, C., Tesauro, C., Desideri, A., & Weightman, P. (2010). Adsorption of the cysteine–tryptophan dipeptide at the Au(110)/liquid interface studied using reflection anisotropy spectroscopy. SURFACE SCIENCE, 604(23-24), 2170-2176 [10.1016/j.susc.2010.09.010]. Dettagli
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  101. Tesauro, C., Fiorani, P., D'Annessa, I., Chillemi, G., Turchi, G., & Desideri, A. (2010). Erybraedin C, a natural compound from the plant Bituminaria bituminosa, inhibits both the cleavage and religation activities of human topoisomerase I. BIOCHEMICAL JOURNAL, 425(3), 531-539. Dettagli
  102. Zazza, C., Coletta, A., Sanna, N., Mancini, G., & Desideri, A. (2010). Solvent Effects on the Valence UV-Vis Absorption Spectra of Topotecan Anticancer Drug in Aqueous Solution at Room Temperature: A Nanoseconds Time-scale TD-DFT/MD Computational Study. JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL, 114(20), 6770-6778. Dettagli
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  104. Bruzzese, F., Rocco, M., Castelli, S., Di Gennaro, E., Desideri, A., & Budillon, A. (2009). Synergistic antitumor effect between vorinostat and topotecan in small cell lung cancer cells is mediated by generation of reactive oxygen species and DNA damage-induced apoptosis. MOLECULAR CANCER THERAPEUTICS, 8(11), 3075-3087. Dettagli
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  107. Ammendola, S., Lembo, A., Battistoni, A., Tagliatesta, P., Ghisalberti, C., & Desideri, A. (2009). 10-Undecanhydroxamic acid, a hydroxamate derivative of the undecanoic acid, has strong antimicrobial activity through a mechanism that limits iron availability. FEMS MICROBIOLOGY LETTERS, 294(1), 61-67 [10.1111/j.1574-6968.2009.01537.x]. Dettagli
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  124. Bordo, D., Pesce, A., , B., Stroppolo, M.E., Falconi, M., & Desideri, A. (2006). Cu,Zn superoxide dismutase in prokaryotes and eukaryotes.. In K. Wieghardt, T. Poulos, & A. Messerschmidt (a cura di), Handbook of Metalloproteins (pp. 1284-1300). John Wiley & Sons, Ltd. London. Dettagli
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  127. De Domenico, I., Lania, A., Bonaccorsi_Di_Patti, M.C., Battistoni, A., Musci, G., & Desideri, A. (2006). Purification and characterization of recombinant Caulobacter crescentus Cu,Zn superoxide dismutase. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 1764(1), 105-109 [10.1016/j.bbapap.2005.08.021]. Dettagli
  128. Fiorani, P., Chillemi, G., Losasso, C., Castelli, S., & Desideri, A. (2006). The different cleavage DNA sequence specificity explains the camptothecin resistance of the human topoisomerase I Glu418Lys mutant. NUCLEIC ACIDS RESEARCH, 34(18), 5093-5100. Dettagli
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  130. Cavallari, M., Desideri, A., Falconi, M., & Ferrario, M. (2005). Molecular dynamics simulations of the Trp repressor–DNA complex and the AV77 mutant. COMPUTER PHYSICS COMMUNICATIONS, 169, 130-134 [10.1016/j.cpc.2005.03.031]. Dettagli
  131. Chillemi, G., Fiorani, P., Castelli, S., Bruselles, A., Benedetti, P., & Desideri, A. (2005). Effect on DNA relaxation of the single Thr718Ala mutation in human topoisomerase I: a functional and molecular dynamics study. NUCLEIC ACIDS RESEARCH, 33(10), 3339-3350. Dettagli
  132. Contessa, G.M., Orsale, M., Melino, S., Torre, V., Paci, M., Desideri, A., et al. (2005). Structure of calmodulin complexed with an olfactory CNG channelfragment and role of the central linker: Residual dipolar couplingsto evaluate calmodulin binding modes outside the kinase family. JOURNAL OF BIOMOLECULAR NMR, 31(3), 185-199. Dettagli
  133. Maragliano, L., Falconi, M., Sergi, A., Cioni, P., Castelli, S., Lania, A., et al. (2005). Experimental and simulative dissociation of dimeric Cu,Zn superoxide dismutase doubly mutated at the intersubunit surface. BIOPHYSICAL JOURNAL, 88, 2875-2882 [10.1529/biophysj.104.057638]. Dettagli
  134. Morozzo Della Rocca, B., Miniero, D., Tasco, G., Dolce, V., Falconi, M., Ludovico, A., et al. (2005). Substrate-induced conformational changes of the mitochondrial oxoglutarate carrier: A spectroscopic and molecular modelling study. MOLECULAR MEMBRANE BIOLOGY, 22, 443-452 [10.1080/09687860500269335]. Dettagli
  135. Sanna, N., Chillemi, G., Grandi, A., Castelli, S., Desideri, A., & Barone, V. (2005). New hints on the pH-driven tautomeric equilibria of the topotecan anticancer drug in aqueous solutions from an integrated spectroscopic and quantum-mechanical approach. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 127(44), 15429-15436. Dettagli
  136. Sennato, S., Bordi, F., Cametti, C., Coluzza, C., Desideri, A., & Rufini, S. (2005). Evidence of domain formation in cardiolipin-glycerophospholipid mixed monolayers. A thermodynamic and AFM study. JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL, 109(33), 15950-15957. Dettagli
  137. Bottini, M., Di Venere, A., Tautz, L., Desideri, A., Lugli, P., Avigliano, L., et al. (2004). Structural Stability of Azurin Encapsulated in Sol-Gel Glasses: A Fluorometric Study. JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY, 30(3), 205-214. Dettagli
  138. Chillemi, G., Redinbo, M., Bruselles, A., & Desideri, A. (2004). Role of the linker domain and the 203-214 N-terminal residues in the human topoisomerase I DNA complex dynamics. BIOPHYSICAL JOURNAL, 87(6), 4087-4097. Dettagli
  139. Falconi, M., Melino, G., & Desideri, A. (2004). Molecular Dynamics Simulation of the C-terminal sterile alpha-motif (SAM) domain of human p73 alpha: evidence of a dynamical relationship between helices 3 and 5. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 316(4), 1037-1042 [10.1016/j.bbrc.2004.02.146]. Dettagli
  140. Garofoli, S., Falconi, M., & Desideri, A. (2004). Thermophilicity of wild type and mutant cold shock proteins by molecular dynamics simulation. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 21, 771-780. Dettagli
  141. Orsale, M.V., Melino, S., Contessa, G.M., Torre, V., Paci, M., Desideri, A., et al. (2003). Calmodulin modulation of the olfactory CNG channel: Solution structure by NMR of a complex between a fragment of the N-terminal domain and calmodulin. Paper presented at 47th Annual Meeting of the Biophysical Society, San Antonio, Texas, USA. Dettagli
  142. Cioni, P., Apesce, B., Morozzo della Rocca, B., Castelli, S., Falconi, M., Parrilli, L., et al. (2003). Active site copper and zinc ions modulate the quaternary structure of prokaryotic Cu,Zn superoxide dismutase. JOURNAL OF MOLECULAR BIOLOGY, 326, 1351-1360. Dettagli
  143. Desideri, A., & Falconi, M. (2003). Prokaryotic Cu/Zn Superoxide Dismutases. BIOCHEMICAL SOCIETY TRANSACTIONS, 31, 1322-1325. Dettagli
  144. Falconi, M., Altobelli, G., Iovino, M.C., Politi, V., & Desideri, A. (2003). A model for matrix metalloproteinase II and collagen interaction: insight from molecular dynamics. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 17, 837-848. Dettagli
  145. Falconi, M., Brunelli, A., Apesce, M., Ferrario, M., Bolognesi, M., & desideri, A. (2003). Static and dynamic water molecules in Cu,Zn superoxide dismutase. PROTEINS, 51, 607-615. Dettagli
  146. Fiorani, P., Bruselles, A., Falconi, M., Chillemi, G., Desideri, A., & Benedetti, P. (2003). Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I. THE JOURNAL OF BIOLOGICAL CHEMISTRY, 278, 43268-43275. Dettagli
  147. Morozzo Della Rocca, B., Lauria, G., Venerini, F., Palmieri, L., Polizio, F., Capobianco, L., et al. (2003). The mitochondrial oxoglutarate carrier: Structural and dynamic properties of transmembrane segment IV studied by site-directed spin labeling. BIOCHEMISTRY, 42, 5493-5499 [10.1021/bi027025q]. Dettagli
  148. Orsale, M., Melino, S., Contessa, G.M., Torre, V., Andreotti, G., Motta, A., et al. (2003). Two distinct calcium-calmodulin interactions with N-terminal regions of the olfactory and rod cyclic nucleotide-gated channels characterized by NMR spectroscopy. FEBS LETTERS, 548(1-3), 11-16. Dettagli
  149. Falconi, M., O'Neill, P., Stroppolo, M.E., & Desideri, A. (2002). Superoxide Dismutase Kinetics, 349, 38-49. Dettagli
  150. Falconi, M., Parrilli, L., Battistoni, A., & Desideri, A. (2002). Protein flexibility in monomeric Cu,Zn superoxide dismutase detected by molecular dynamics simulation and limited proteolysis. PROTEINS, 47, 513-520. Dettagli
  151. Militello V., L.M. (2002). Local dynamic properties of the heme pocket in native and solvent-induced molten-globule-like states of cytochrome c. BIOPHYSICAL CHEMISTRY, 97(2009/03/02 00:00:00.000), 121-128. Dettagli
  152. Sergi, A., Ciccotti, G., Falconi, M., Desideri, A., & Ferrario, M. (2002). Effective binding force calculation in a dimeric protein by molecular dynamics simulation. THE JOURNAL OF CHEMICAL PHYSICS, 116, 6329-6338. Dettagli
  153. Bongiovanni C., F.T. (2001). An electrochemical multienzymatic biosensor for determination of cholesterol. BIOELECTROCHEMISTRY, 54(1), 17-22. Dettagli
  154. Falconi, M., Cambria, M.T., Cambria, A., & Desideri, A. (2001). Structure and stability of the insulin dimer investigated by molecular dynamics simulation. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 18, 761-772 [10.1080/07391102.2001.10506705]. Dettagli
  155. Falconi, M., Stroppolo, M.E., Cioni, P., Sergi, A., Ferrario, M., & Desideri, A. (2001). Dynamics-function correlation in Photobacterium leiognathi Cu,Zn superoxide dismutase: a spectroscopic and molecular dynamics simulation study. BIOPHYSICAL JOURNAL, 80, 2556-2567. Dettagli
  156. Iovino, M., Falconi, M., Marcellini, A., & Desideri, A. (2001). Molecular dynamics simulation of the antimicrobial salivary peptide histatin-5 in water and in trifluoroethanol. JOURNAL OF PEPTIDE RESEARCH, 58, 45-55. Dettagli
  157. Iovino, M., Falconi, M., Petruzzelli, R., & Desideri, A. (2001). Role of the helix capping in the stability of the mouse prion (180-213) segment: investigation through molecular dynamics simulations. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 19, 237-246. Dettagli
  158. Pacello, F., Langford, P.R., Kroll, J.S., Indiani, C., Sinulevich, G., Desideri, A., et al. (2001). A Novel Heme Protein, the Cu,Zn-Superoxide Dismutase from Haemophilus ducreyi. THE JOURNAL OF BIOLOGICAL CHEMISTRY, 276(32), 30326-30334 [10.1074/jbc.M010488200]. Dettagli
  159. Sinibaldi F., F.L. (2001). Cytochrome c reconstituted from two peptide fragments displays native-like redox properties. EUROPEAN JOURNAL OF BIOCHEMISTRY, 268(16), 4537-4543. Dettagli
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