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Professore Ordinario di Anatomia dal 2019 presso la Facoltà di Medicina e Chirurgia dove insegna Anatomia 1 (Cardio-Splancnologia) e Anatomia 2 (Neuroanatomia) nel C.L. di Medicina e Chirurgia e Medicine and Surgery; Anatomia Umana nel il C.L. di Biotecnologie; Human Anatomy nel C.L. Physical Activity and Health Promotion. È stata Professore Associato di Anatomia Umana (2000-2019) e Ricercatore Universitario (1993-2000) presso la Facoltà di Medicina e Chirurgia dell’Università di Roma Tor Vergata. Ha conseguito Dottorato di Ricerca in Scienze Morfogenetiche e Citologiche presso Sapienza Università di Roma nel 1991 (3°Ciclo). Ha frequentato la scuola di specializzazione in Oncologia Molecolare presso l’Università de L’Aquila (1992-93). È stata Visiting Scientist presso il Mammalian Genetics Laboratory del National Cancer Institute Frederick MD, U.S.A. (1990-1993) dove ha identificato i fattori di crescita essenziali per lo sviluppo delle cellule germinali primordiali di mammifero. È stata Research Associate press il Gurdon Institute, University of Cambridge, UK (1998). Si è laureata in Medicina e Chirurgia con lode mettendo a punto un protocollo di  fecondazione interspecifica tra ovociti di hamster e spermatozoi umani, definito Hamster test, presso Sapienza Università di Roma (1985). E’ Coordinatrice del Corso di Dottorato in Biotecnologie Medico-Chirurgiche e Medicina Traslazionale dall’AA. 2021-2022.   Pubblicazioni scientifiche 2014-2024 1)    Carosa E, Castri A, Forcella C, Sebastiani G, Di Sante S, Gravina GL, Ronchi P, Cesarini V, Dolci S, Di Stasi S, Lenzi A, Jannini EA. (2014) Platelet-derived growth factor regulation of type-5 phosphodiesterase in human and rat penile smooth muscle cells.J Sex Med. 11:1675-84. 3.1 2)    Faraoni I, Compagnone M, Lavorgna S, Angelini DF, Cencioni MT, Piras E, Panetta P, Ottone T, Dolci S, Venditti A, Graziani G, Lo-Coco F. (2015) BRCA1, PARP1 and γH2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib. Biochem Biophys Acta. 1852:462-72. 4,9 3)    Tassinari V, Campolo F, Cesarini V, Todaro F, Dolci S, Rossi P. (2015) Fgf9 inhibition of meiotic differentiation in spermatogonia is mediated by Erk-dependent activation of Nodal-Smad2/3 signaling and is antagonized by Kit Ligand. Cell Death Dis. 12;6:e1688  5.2 4)    Desimio MG, Campolo F, Dolci S, De Felici M, Farini D (2015) SOHLH1 and SOHLH2 directly down-regulate stimulated by retinoic acid 8 (STRA8) expression. Cell Cycle. 14:1036-45. 4. 5)    Dolci S, Campolo F, De Felici M. (2015) Gonadal development and germ cell tumors in mouse and humans. Semin Cell Dev Biol. 45:114-23. 5.9 6)    Cesarini V., Martini M., Ricci Vitiani L., Gravina GG., Di Agostino S., Graziani G., D’Alessandris   Q.A., Pallini P., Larocca L.M., Rossi P., Jannini E.A., and S. Dolci (2017).Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome. Oncotarget. Feb 21; (8):13223-13239. 7)    Cesarini V, Guida E, Todaro F, Di Agostino S, Tassinari V, Nicolis S, Favaro R, Caporali S, Lacal PM, Botti E, Costanzo A, Rossi P, Jannini EA, Dolci S. (2017) Sox2 is not required for melanomagenesis, melanoma growth and melanoma metastasis in vivo.Oncogene. Aug;36(31):4508-4515. doi: 10.1038/onc.2017.53. Epub 2017 Apr 3. 8)    De Domenico E, Todaro F, Rossi G, Dolci S, Geremia R, Rossi P, Grimaldi P. Overactive type 2 cannabinoid receptor induces meiosis in fetal gonads and impairs ovarian reserve (2017). Cell Death Dis. Oct 5;8(10):e3085. doi: 10.1038/cddis.2017.496. 9)    Gravina GL, Marampon F, Sanità P, Festuccia C, Forcella C, Scarsella L, Jitariuc A, Vetuschi A, Sferra R, Colapietro A, Carosa E, Dolci S, Lenzi A, Jannini EA. Episode-like pulse testosterone supplementation induces tumor senescence and growth arrest down-modulating androgen receptor through modulation of p-ERK1/2, pARser81 and CDK1 signaling: biological implications for men treated with testosterone replacement therapy. (2017). Oncotarget. Nov 30;8(69):113792-113806. doi: 10.18632/oncotarget.22776.  10) Di Siena S, Campolo F, Gimmelli R, Di Pietro C, Marazziti D, Dolci S, Lenzi A, Nussenzweig A, Pellegrini M. Atm reactivation reverses ataxia telangiectasia phenotypes in vivo. Cell Death Dis. 2018 Feb 22;9(3):314. doi: 10.1038/s41419-018-0357-8. PMID: 29472706 11) Balistreri CR, Pisano C, Bertoldo F, Massoud R, Dolci S, Ruvolo G. (2019). Red Blood Cell Distribution Width, Vascular Aging Biomarkers, and Endothelial Progenitor Cells for Predicting Vascular Aging and Diagnosing/Prognosing Age-Related Degenerative Arterial Diseases. Oct;22(5):399-408. doi: 10.1089/rej.2018.2144. 12) Todaro F, Campolo F, Barrios F, Pellegrini M, Di Cesare S, Tessarollo L, Rossi P, Jannini EA, Dolci S. (2019). Regulation of Kit Expression in Early Mouse Embryos and ES Cells. Stem Cells. Mar;37(3):332-344. doi: 10.1002/stem.2960. 13) Cesarini V, Pisano C, Rossi G, Balistreri CR, Botti F, Antonelli G, Ruvolo G, Jannini EA, Dolci S.(2019).Regulation of PDE5 expression in human aorta and thoracic aortic aneurysms.Sci Rep. 2019 Aug 21;9(1):12206. doi: 10.1038/s41598-019-48432-6. 14) Bisegna C, Gravina GL, Pierconti F, Martini M, Larocca L, Rossi P, Grimaldi P, Dolci S, Di Stasi S, Jannini EA. (2020). Regulation of PDE5 expression in normal prostate, benign prostatic hyperplasia, and adenocarcinoma. Andrology. Mar;8(2):427-433. doi: 10.1111/andr.12695. 15) Barchi M, Innocenzi E, Giannattasio T, Dolci S, Rossi P, Grimaldi P. (2019) Cannabinoid Receptors Signaling in the Development, Epigenetics, and Tumours of Male Germ Cells. Int J Mol Sci. Dec 18;21(1):25. doi: 10.3390/ijms2101025. 16) Gaggi G, Di Credico A, Izzicupo P, Sancilio S, Di Mauro M, Iannetti G, Dolci S, Amabile G, Di Baldassarre A, Ghinassi B. (2020) Decellularized Extracellular Matrices and Cardiac Differentiation: Study on Human Amniotic Fluid-Stem Cells. Int J Mol Sci. Aug 31;21(17):6317. doi: 10.3390/ijms21176317. 17) Cesarini V, Guida E, Campolo F, Crescioli C, Di Baldassarre A, Pisano C, Balistreri CR, Ruvolo G, Jannini EA, Dolci S. (2020).Type 5 phosphodiesterase (PDE5) and the vascular tree: From embryogenesis to aging and disease. Mech Ageing Dev. Sep;190:111311. doi: 10.1016/j.mad.2020.111311. Epub 2020 Jul 3. 18) Caggiano C., Guida E., Todaro F., Bielli P.,  Mori M., Ghirga F., Quaglio D., Botta B.,  Moretti F., Grimaldi P., Jannini E.A., Barchi M., Dolci S. (2020) Sempervirine inhibits RNA polymerase I transcription independently from p53 in tumor cells. Cell Death Discov. Oct 28;6(1):111. doi: 10.1038/s41420-020-00345-4. 19) Barchi, M., Bielli, P., Dolci, S., Rossi, P., Grimaldi, P. (2020). Non-coding RNAs and splicing activity in testicular germ cell tumors. Life 11(8), 736 20) De Felici, M., Klinger, F.G., Campolo, F., Barchi, M., Dolci, S. To be or not to be a germ cell: The extragonadal germ cell tumor paradigm. International Journal of Molecular Sciences, 2021, 22(11), 5982 21) Barchi M, Guida E, Dolci S, Rossi P, Grimaldi P. Endocannabinoid system and epigenetics in spermatogenesis and testicular cancer. Vitam Horm. 2023;122:75-106. 22) Sansone A, Reisman Y, Meto S, Dolci S, Jannini EA.The Role of the "Anti-Inflammatory" Couple for the Management of Hyperuricemia With Deposition. J. Sex Med. 2022 Oct;10(5):100562. 23) Tassinari V, La Rosa P, Guida E, Colopi A, Caratelli S, De Paolis F, Gallo A, Cenciarelli C, Sconocchia G, Dolci S, Cesarini V. Contribution of A-to-I RNA editing, M6A RNA Methylation, and Alternative Splicing to physiological brain aging and neurodegenerative diseases (2023). Mech Ageing Dev. 212:111807. 24) Colopi A, Fuda S, Santi S, Onorato A, Cesarini V, Salvati M, Balistreri CR, Dolci S, Guida E. Impact of age and gender on glioblastoma onset, progression, and management (2023) Mech Ageing Dev. 2023;211:111801. 25) Da Ros V, Oddo L, Toumia Y, Guida E, Minosse S, Strigari L, Strolin S, Paolani G, Di Giuliano F, Floris R, Garaci F, Dolci S, Paradossi G, Domenici F.(2023). PVA-Microbubbles as a Radioembolization Platform: Formulation and the In Vitro Proof of Concept. Pharmaceutics 15(1):217. 26) Wang F, Colonnello E, Zhang H, Sansone A, Wang C, Dolci S, Guo J, Jannini EA.Comparing Western and traditional Chinese medicine for male sexual dysfunction: can Klotho represent a silk road? (2023) Andrology. doi: 10.1111/andr.13580.      

Full Professor of Anatomy since 2019 at the Faculty of Medicine and Surgery where she teaches Anatomy 1 (Cardio-Splanchnology) and Anatomy 2 (Neuroanatomy) in the C.L. of Medicine and Surgery and Medicine and Surgery; Human Anatomy in the C.L. of Biotechnology; Human anatomy in the C.L. Physical activity and health promotion. Associate Professor of Human Anatomy (2000-2019) and Assistant Researcher (1993-2000) at the Faculty of Medicine and Surgery of the University of Rome Tor Vergata. She obtained her PhD in Morphogenetic and Cytological Sciences at Sapienza University of Rome in 1991 (3rd cycle). She attended the residency in Molecular Oncology at the University of L'Aquila (1992-93). Visiting Scientist at the Mammalian Genetics Laboratory of the National Cancer Institute Frederick MD, U.S.A. (1990-1993) where she identified  the growth factors essential for the development of mammalian primordial germ cells. Research Associate at the Gurdon Institute, University of Cambridge, UK (1998). She graduated in Medicine and Surgery with a thesis on interspecific fertilization between hamster oocytes and human spermatozoa at Sapienza University of Rome (1985). She is the actual Coordinator of the Doctoral Course in Medical-Surgical Biotechnology and Translational Medicine since the AA. 2021-2022. References  2014-2024 1)    Carosa E, Castri A, Forcella C, Sebastiani G, Di Sante S, Gravina GL, Ronchi P, Cesarini V, Dolci S, Di Stasi S, Lenzi A, Jannini EA. (2014) Platelet-derived growth factor regulation of type-5 phosphodiesterase in human and rat penile smooth muscle cells.J Sex Med. 11:1675-84. 3.1 2)    Faraoni I, Compagnone M, Lavorgna S, Angelini DF, Cencioni MT, Piras E, Panetta P, Ottone T, Dolci S, Venditti A, Graziani G, Lo-Coco F. (2015) BRCA1, PARP1 and γH2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib. Biochem Biophys Acta. 1852:462-72. 4,9 3)    Tassinari V, Campolo F, Cesarini V, Todaro F, Dolci S, Rossi P. (2015) Fgf9 inhibition of meiotic differentiation in spermatogonia is mediated by Erk-dependent activation of Nodal-Smad2/3 signaling and is antagonized by Kit Ligand. Cell Death Dis. 12;6:e1688  5.2 4)    Desimio MG, Campolo F, Dolci S, De Felici M, Farini D (2015) SOHLH1 and SOHLH2 directly down-regulate stimulated by retinoic acid 8 (STRA8) expression. Cell Cycle. 14:1036-45. 4. 5)    Dolci S, Campolo F, De Felici M. (2015) Gonadal development and germ cell tumors in mouse and humans. Semin Cell Dev Biol. 45:114-23. 5.9 6)    Cesarini V., Martini M., Ricci Vitiani L., Gravina GG., Di Agostino S., Graziani G., D’Alessandris   Q.A., Pallini P., Larocca L.M., Rossi P., Jannini E.A., and S. Dolci (2017).Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome. Oncotarget. Feb 21; (8):13223-13239. 7)    Cesarini V, Guida E, Todaro F, Di Agostino S, Tassinari V, Nicolis S, Favaro R, Caporali S, Lacal PM, Botti E, Costanzo A, Rossi P, Jannini EA, Dolci S. (2017) Sox2 is not required for melanomagenesis, melanoma growth and melanoma metastasis in vivo.Oncogene. Aug;36(31):4508-4515. doi: 10.1038/onc.2017.53. Epub 2017 Apr 3. 8)    De Domenico E, Todaro F, Rossi G, Dolci S, Geremia R, Rossi P, Grimaldi P. Overactive type 2 cannabinoid receptor induces meiosis in fetal gonads and impairs ovarian reserve (2017). Cell Death Dis. Oct 5;8(10):e3085. doi: 10.1038/cddis.2017.496. 9)    Gravina GL, Marampon F, Sanità P, Festuccia C, Forcella C, Scarsella L, Jitariuc A, Vetuschi A, Sferra R, Colapietro A, Carosa E, Dolci S, Lenzi A, Jannini EA. Episode-like pulse testosterone supplementation induces tumor senescence and growth arrest down-modulating androgen receptor through modulation of p-ERK1/2, pARser81 and CDK1 signaling: biological implications for men treated with testosterone replacement therapy. (2017). Oncotarget. Nov 30;8(69):113792-113806. doi: 10.18632/oncotarget.22776.  10) Di Siena S, Campolo F, Gimmelli R, Di Pietro C, Marazziti D, Dolci S, Lenzi A, Nussenzweig A, Pellegrini M. Atm reactivation reverses ataxia telangiectasia phenotypes in vivo. Cell Death Dis. 2018 Feb 22;9(3):314. doi: 10.1038/s41419-018-0357-8. PMID: 29472706 11) Balistreri CR, Pisano C, Bertoldo F, Massoud R, Dolci S, Ruvolo G. (2019). Red Blood Cell Distribution Width, Vascular Aging Biomarkers, and Endothelial Progenitor Cells for Predicting Vascular Aging and Diagnosing/Prognosing Age-Related Degenerative Arterial Diseases. Oct;22(5):399-408. doi: 10.1089/rej.2018.2144. 12) Todaro F, Campolo F, Barrios F, Pellegrini M, Di Cesare S, Tessarollo L, Rossi P, Jannini EA, Dolci S. (2019). Regulation of Kit Expression in Early Mouse Embryos and ES Cells. Stem Cells. Mar;37(3):332-344. doi: 10.1002/stem.2960. 13) Cesarini V, Pisano C, Rossi G, Balistreri CR, Botti F, Antonelli G, Ruvolo G, Jannini EA, Dolci S.(2019).Regulation of PDE5 expression in human aorta and thoracic aortic aneurysms. Sci Rep. 2019 Aug 21;9(1):12206. doi: 10.1038/s41598-019-48432-6. 14) Bisegna C, Gravina GL, Pierconti F, Martini M, Larocca L, Rossi P, Grimaldi P, Dolci S, Di Stasi S, Jannini EA. (2020). Regulation of PDE5 expression in normal prostate, benign prostatic hyperplasia, and adenocarcinoma. Andrology. Mar;8(2):427-433. doi: 10.1111/andr.12695. 15) Barchi M, Innocenzi E, Giannattasio T, Dolci S, Rossi P, Grimaldi P. (2019) Cannabinoid Receptors Signaling in the Development, Epigenetics, and Tumours of Male Germ Cells. Int J Mol Sci. Dec 18;21(1):25. doi: 10.3390/ijms2101025. 16) Gaggi G, Di Credico A, Izzicupo P, Sancilio S, Di Mauro M, Iannetti G, Dolci S, Amabile G, Di Baldassarre A, Ghinassi B. (2020) Decellularized Extracellular Matrices and Cardiac Differentiation: Study on Human Amniotic Fluid-Stem Cells. Int J Mol Sci. Aug 31;21(17):6317. doi: 10.3390/ijms21176317. 17) Cesarini V, Guida E, Campolo F, Crescioli C, Di Baldassarre A, Pisano C, Balistreri CR, Ruvolo G, Jannini EA, Dolci S. (2020).Type 5 phosphodiesterase (PDE5) and the vascular tree: From embryogenesis to aging and disease. Mech Ageing Dev. Sep;190:111311. doi: 10.1016/j.mad.2020.111311. Epub 2020 Jul 3. 18) Caggiano C., Guida E., Todaro F., Bielli P.,  Mori M., Ghirga F., Quaglio D., Botta B.,  Moretti F., Grimaldi P., Jannini E.A., Barchi M., Dolci S. (2020) Sempervirine inhibits RNA polymerase I transcription independently from p53 in tumor cells. Cell Death Discov. Oct 28;6(1):111. doi: 10.1038/s41420-020-00345-4. 19) Barchi, M., Bielli, P., Dolci, S., Rossi, P., Grimaldi, P. (2020). Non-coding RNAs and splicing activity in testicular germ cell tumors. Life 11(8), 736 20) De Felici, M., Klinger, F.G., Campolo, F., Barchi, M., Dolci, S. To be or not to be a germ cell: The extragonadal germ cell tumor paradigm. International Journal of Molecular Sciences, 2021, 22(11), 5982 21) Barchi M, Guida E, Dolci S, Rossi P, Grimaldi P. Endocannabinoid system and epigenetics in spermatogenesis and testicular cancer. Vitam Horm. 2023;122:75-106. 22) Sansone A, Reisman Y, Meto S, Dolci S, Jannini EA.The Role of the "Anti-Inflammatory" Couple for the Management of Hyperuricemia With Deposition. J. Sex Med. 2022 Oct;10(5):100562. 23) Tassinari V, La Rosa P, Guida E, Colopi A, Caratelli S, De Paolis F, Gallo A, Cenciarelli C, Sconocchia G, Dolci S, Cesarini V. Contribution of A-to-I RNA editing, M6A RNA Methylation, and Alternative Splicing to physiological brain aging and neurodegenerative diseases (2023). Mech Ageing Dev. 212:111807. 24) Colopi A, Fuda S, Santi S, Onorato A, Cesarini V, Salvati M, Balistreri CR, Dolci S, Guida E. Impact of age and gender on glioblastoma onset, progression, and management (2023) Mech Ageing Dev. 2023;211:111801. 25) Da Ros V, Oddo L, Toumia Y, Guida E, Minosse S, Strigari L, Strolin S, Paolani G, Di Giuliano F, Floris R, Garaci F, Dolci S, Paradossi G, Domenici F.(2023). PVA-Microbubbles as a Radioembolization Platform: Formulation and the In Vitro Proof of Concept. Pharmaceutics 15(1):217. 26) Wang F, Colonnello E, Zhang H, Sansone A, Wang C, Dolci S, Guo J, Jannini EA.Comparing Western and traditional Chinese medicine for male sexual dysfunction: can Klotho represent a silk road? (2023) Andrology. doi: 10.1111/andr.13580.      

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