Gargioli Cesare
Carriera Scolastica
13/07/2005
PhD in Biologia e Biochimica presso il Centro di Medicina Rigenerativa,Dipartimento di Biologia e Biochimica, Università di Bath, UK.
01/03/2000
Laurea in Biologia “Summa cum Laude” presso l’Università di Roma “Tor Vergata”, IT.
Attività di ricerca
02/03/2000-31/08/2001
Vincitore della Borsa di Studio neo-laureati Tor Vergata-IRBM presso l'Istituto di Ricerche di Biologia Molecolare Pomezia - IRBM P. Angeletti, Pomezia (RM); in particolare lavorando su un progetto di terapia genica sfruttando un nuovo sistema di attivazione trascrizionale basato sul sistema "quorum sensing".
21/09/2001-21/10/2001
Corso internazionale sulla salute e manipolazione di piccoli e grandi mamiferi.
Animal Health Office, UK
21/09/2001-20/09/2004
Studente di PhD nel laboratorio del Prof. J.W.M. Slack presso il Centre for Regenerative Medicine, Department of Biology and Biochemistry, University of Bath, UK, conseguendo il titolo di PhD presentando il lavoro di tesi dal titolo: Analysis of cell lineage stability during tail regeneration in X. laevis tadpoles.
01/02/2005-31/08/2009
Assegnista per l’Università degli Studi di ROMA "La Sapienza" - Roma; durante l'incarico il candidato ha svolto la sua attività di ricerca presso il laboratorio del Prof. G. Cossu nell'istituto di Biologia Cellulare e Ingegneria Tissutale del Parco Scientifico del S. Raffaele in Roma. Ha svolto l’attività di ricerca nel campo delle Cellule Staminali e della Medicina Rigenerativa, studiando la rigenerazione e ricostruzione 3D di muscolo scheletrico e la terapia cellulare per la cura della distrofia muscolare. Inoltre il candidato ha collaborato, nell'ambito del progetto europeo FP7 "ANGIOSCAFF", con vari gruppi internazionali di ricerca nell’ambito dell’ingegneria tissutale e delle biotecnologie delle matrici biomimetiche.
01/04/2010-30/06/2012
Senior Scientist presso il laboratorio di Anatomia Comparata del Prof. S. Cannata dell'Università degli Studi di ROMA "Tor Vergata". Durante questo periodo il candidato si è impegnato in ricerche nell'ambito dell’Ingegneria Tissutale del muscolo scheletrico e della tecnologia di nuove matrici biomimetiche come supporti per la rigenerazione del muscolo.
01/07/2012-31/12/2013
Partecipazione come Senior Scientist all'attività di ricerca del laboratorio di Rigenerazione Tissutale della Dr.ssa C. Bearzi presso l'istituto IRCCS Multimedica, Milano, IT, ottenendo risultati su matrici biomimetiche per il differenziamento miogenico.
15/01/2014 ad oggi
Ricercatore a t.d. - t.pieno (art. 24 c.3-a L. 240/10) per il gruppo del Prof. Gianni Cesareni presso il dipartimento di Biologia dell' Università degli Studi di Roma "Tor Vergata". Durante l'incarico il candidato ha svolto e sta ancora svolgendo attività di ricerca nel campo dell’analisi dell’eterogeneità delle popolazioni mononucleari del muscolo scheletrico e in quello delle nuove tecnologie per l'Ingegneria Tissutale del Muscolo Scheletrico come l'uso di stampanti 3D e Bio-Inchiostri.
Organizzazione o partecipazione come relatore a convegni
18/09/2004-23/09/2004
Cellular and Molecular Basis of Regeneration, San Feliu de Guixols, Spain. Title “Muscle satellite cells and myofibers reformation during Xenopus tail regeneration”
22/04/2012-24/04/2012
“CMD Myomatrix Conference”, at the University of Reno, Nevada. Title “Autologous progenitor cells in a hydrogel form a supernumerary and functional skeletal muscle in vivo “
18/04/2013
ISMuLT Scientific Workshop on stem cells for ligament and tendon tissue engineering and regeneration. Title “ In vivo generation of an artificial functional skeletal muscle”
24/09/2015
ISMuLT Scientific Workshop on biomaterials and regenerative medicine for the musculoskeletal system. Title “ Muscle derived pericytes for artificial skeletal muscle human-like size”
09/12/2016-10/12/2016
XVIII Congresso Nazionale I.O.R.S. (Italian Orthopaedic Research Society) “La rigenerazione nell’apparato Muscoloscheletrico” Roma, 9 – 10 dicembre 2016. Invitato come relatore nella Sessione: I Tessuto Muscolare con la presentazione dal titolo: "Strategie innovative per la
ricostruzione delle grandi perdite di tessuto muscolare".
12/06/2017-15/06/2017
Membro del comitato organizzativo del 63° Convegno del Gruppo Embriologico Italiano. Roma, 12-15 Giugno 2017.
12/10/2017-15/10/2017
Organizzazione del 14° Meeting dell'Istituto Interuniversitario di Miologia (IIM) come membro del Consiglio Scientifico dell’IIM
11/10/2018-14/10/2018
Organizzazione del 15° Meeting dell'Istituto Interuniversitario di Miologia (IIM) come membro del Consiglio Scientifico dell’IIM
Responsabilità scientifica di finanziamenti
01/01/2010-01/01/2011
Responsabile dello sviluppo di prototipi di ingegneria tissutale nell'ambito del progetto europeo Angioscaff: Prototype validation support grant from the Angioscaff large scale FP7 collaborative project on angiogenesis and tissue engineering.
01/01/2010-01/01/2013
Coordinatonatore insieme al Prof. G. Cossu presso l'istituto di Biologia Cellulare e Ingegneria Tissutale del Parco Scientifico del S. Raffaele in Roma, l’Unità 3 del progetto “Stem cell based approaches to monogenic diseases” finanziato dalla Fondazione Roma in particolare concentrando lo studio su nuove strategie per la terapia cellulare come cura delle distrofie muscolari: Immortalizzazione reversibile di mesoangioblasti umani.
01/01/2013
Responsabile di unità di ricerca per il progetto: Infrastruttura Italiana di Medicina Rigenerativa (IRMI). Italian PON: National Cluster of Life Science “Alisei”
01/01/2015-30/06/2016
Responsabile di unità di ricerca (P.I.) per il progetto: MD-ESMPLAT- Developing an artificial muscle tissues system as a platform to screen and test in vivo novel pharmacological therapies for muscular dystrophies patients. Finanziato dall'università di Tor Vergata Uncovering excellence funding scheme.
01/01/2016-01/01/2019
2023-25 Responsabile di unità (P.I.) per il bando PRIN: Systems vaccinology and innovative immunological approaches to investigate the impact of biological sex on COVID-19 mRNA vaccine immunogenicity, reactogenicity, and safety.
2021-23: Unità di Ricerca PO FESR LAZIO 2014/2020 “Lazio Innova”: BIOPMEAT.
2019-22: Coordinatore e PI del progetto RicostruzionE del tesSUto Muscolare scheletricO on mio-strutture stampate in 3D “RESUMO” Ministero della Difesae, PNRM (Piano Nazionale Ricerca Militare)
2019-22: Responsabile di unità (P.I.) per il bando PRIN: 3D Muscle-Tendon Unit Modelling for Unravelling Tissue Crosstalk in Muscular Dystrophies and Aging.
2016-19 Responsabile di unità (P.I.) per il bando PRIN : Targeting autophagy in myogenic cells to counteract muscle aging and diseases: novel bioengineering tools for validating pharmacological candidates.
Publicazioni selezionate
1. Gargioli C. and Slack J.M.W. Cell lineage tracing during Xenopus tail regeneration. Development 2004 Jun; 131 (11): 2669-79 2. Gargioli C, Coletta M, De Grandis F, Cannata SM, and Cossu G. PlGF-MMP9 expressing cells restore microcirculation and efficacy of cell therapy in old dystrophic muscle. Nat Med. 2008 Sep 14(9):97 3. Fuoco C, Biondo A, Salvatori ML, Shapira-Schweitzer K, Santoleri S, Bernardini S, Cannata S, Seliktar D, Cossu G and Gargioli C.Injectable PEG-fibrinogen improves survival and differentiation of transplanted myogenic progenitors in acute and chronic skeletal muscle degeneration. Skelet Muscle 2012; 26;2(1):24. 4. Fuoco C,Sangalli E, Vono R, Testa S, Sacchetti B, Bernardini S, Madeddu P, Cesareni G, Seliktar D,Rizzi R, Bearzi C, Cannata S M, Spinetti Gand Gargioli C.3D hydrogel environment rejuvenates aged pericytes for skeletal muscle tissue engineering. Front Physiol. 2014 May 30;5:203. 5. Fuoco C, Biondo A, Longa E, Mascaro A, Shapira-Schweitzer K, Salvatori M L, Santoleri S, Testa S, Bernardini S, Cannata S M, Bottinelli R, Seliktar D, Cossu G and Gargioli C. In vivo generation of an entire, functional skeletal muscle.EMBO Mol Med. 2015 Feb 25. pii: e201404062
6. Vono R, Fuoco C, Testa S, Pirrò S, Maselli D, Mc Collough DF, Sangalli E, Pintus G, Giordo R, Finzi G, Sessa F, Cardani R, Gotti A, Losa S, Cesareni G, Rizzi R, Bearzi C, Cannata S, Spinetti G, Gargioli C, Madeddu P. Activation of the Pro-Oxidant PKCβII-p66Shc Signaling Pathway Contributes to Pericyte Dysfunction in Skeletal Muscles of Diabetic Patients with Critical Limb Ischemia.Diabetes. 2016 Sep 6. pii: db160248. 7. Testa S, Costantini M, Bernardini S, Trombetta M, Seliktar D, Cannata S, Rainer A and Gargioli C.Combination of biochemical and mechanical cues for tendon tissue engineering. J Cell Mol Med. 2017 May 4. 8. Costantini M, Testa S, Mozetic P, Barbetta A, Fornaretti E, Tamiro F, Jaroszewicz J, SÌwięszkowski W, Trombetta M, Seliktar D, Garstecki P, Cesareni G, Cannata S, Rainer A and Gargioli C.Microfluidically enhanced 3D bioprinting of highly aligned hydrogel structures for in vitro and in vivo fabrication of artificial muscle tissue. Biomaterials. 2017 Jul;131:98-110. 9. Errico V, Arrabito G, Fornetti E, Fuoco C, Testa S, Saggio G, Rufini S, Cannata S, Desideri A, Falconi C, Gargioli C. High-Density ZnO Nanowires as a Reversible Myogenic-Differentiation Switch. ACS Appl Mater Interfaces. 2018 Apr 25;10(16):14097-14107.
10. Testa S, Riera CS, Fornetti E, Riccio F, Fuoco C, Bernardini S, Baldi J, Costantini M, Foddai ML, Cannata S, Gargioli C. Skeletal Muscle-Derived Human Mesenchymal Stem Cells: Influence of Different Culture Conditions on Proliferative and Myogenic Capabilities. Front Physiol. 2020 Sep 16;11:553198.
11. Costantini M, Testa S, Fornetti E, Fuoco C, Sanchez Riera C, Nie M, Bernardini S, Rainer A, Baldi J, Zoccali C, Biagini R, Castagnoli L, Vitiello L, Blaauw B, Seliktar D, Święszkowski W, Garstecki P, Takeuchi S, Cesareni G, Cannata S, Gargioli C. Biofabricating murine and human myo-substitutes for rapid volumetric muscle loss restoration. EMBO Mol Med. 2021 Feb 15:e12778.
12. Fornetti E, Testa S, De Paolis F, Fuoco C, Bernardini S, Pozo Devoto V, Stokin G B, Giannitelli S M, Rainer A, Bigot A, Zoccali C, Baldi J, Sandonà D, Rizzi R, Bearzi C, Forte G, Cannata S, Gargioli C.Dystrophic Muscle Affects Motoneuron Axon Outgrowth and NMJ Assembly. Advanced Materials Technologies 2022 March.
13. Reggio A, De Paolis F, Bousselmi S, Cicciarelli F, Bernardini S, Rainer A, Seliktar D, Testa S, Cirillo C, Grumati P, Cannata S, Fuoco C, Gargioli C. A 3D adipogenesis platform to study the fate of fibro/adipogenic progenitors in muscular dystrophies. Dis Model Mech. 2023 Jun 1;16(6)
14. De Paolis F, Testa S, Guarnaccia G, Reggio A, Fornetti E, Cicciarelli F, Deodati R, Bernardini S, Peluso D, Baldi J, Biagini R, Bellisari FC, Izzo A, Sgalambro F, Arrigoni F, Rizzo F, Cannata S, Sciarra T, Fuoco C, Gargioli C. Long-term longitudinal study on swine VML model. Biol Direct. 2023 Jul 31;18(1):42.
15. Fornetti E, De Paolis F, Fuoco C, Bernardini S, Giannitelli SM, Rainer A, Seliktar D, Magdinier F, Baldi J, Biagini R, Cannata S, Testa S, Gargioli C.A novel extrusion-based 3D bioprinting system for skeletal muscle tissue engineering. Biofabrication. 2023 Feb 3;15(2).
GARGIOLI Cesare A. PERSONAL STATEMENT Associate Professor at Department of Biology, Rome University Tor Vergata. He published 75 publications in peer reviewed journal (29 as first or last/corresponding author) among which several in high impact journal likewise Nature Medicine, EMBO Mol Med and Biomaterials. Total H index 23 (SCOPUS); i10-hindex 44 (Google scholar). He directs the laboratory of Comparative Anatomy and Tissue Engineering focusing on tissue regeneration and skeletal muscle reconstruction employing biomimetic matrices and 3D printing novel technology. His research has been financed by MIUR (PRIN Program) and Italian Defense Ministry (PNRM). B. EDUCATION, TRAINING AND ACADEMIC CAREER 2000: Degree in Biological Sciences (summa cum laude), University of Rome Tor Vergata, IT. 2000-01: Research Assistant, Department of Biochemistry, IRBM (P. Angeletti), IT. 2001-04: PhD student in Developmental Biology, Centre of Regenerative Medicine, University of Bath, UK. 2004-05: Post-doctoral fellow Institute of Cell Biology and Tissue Engineering, S. Raffaele Biomedical Park Foundation, Rome, IT.
2005-09: Senior Research Associate, Institute of Cell Biology and Tissue Engineering, S. Raffaele Biomedical Park Foundation, Rome, IT. 2010-12: Assistant Professor, Department of Biology, Rome University Tor Vergata, IT. 2012-14: Researcher, IRCCS Multimedica, Milan, IT. 2014-19: Fixed Term Researcher, Department of Biology, Rome University Tor Vergata, IT.
2019-22 Tenure track Researcher, Department of Biology, Rome University Tor Vergata, IT.
2022- present: Associate Professor, Department of Biology, Rome University Tor Vergata, IT. C. COMMISSIONS OF TRUST
2012-present: Reviewer for international journal: Biomaterials, Acta Biomaterialia, Biofabrication,
Oncotarget, Scientific Report, Stem Cells, Current Gene Therapy, Stem Cell Research and Therapy,
Frontiers, Open FEBS, JBEI, Regenerative Medicine, Drug Delivery 2015-present: Reviewer for funding agency: Swiss National Science Foundation, FWO and Agencie
Nationalle de la Recherche(ANR), KU Leuven, Dutch Parent Project. 2020-present: Member of PhD school Molecular and cellular Biology college at Rome University Tor
Vergata.
D. HONORS AND AWARDS 2000: Graduated with honors (110/110 cum laude) in Biology. 2000-01: “Tor Vergata” University/IRBM Young Biologist Studentship. 2001-04: Welcome Trust Prize Studentship. 2004: 2nd Development/Welcome Picture Prize 2005-09: Research Competitive 2012: Chancellor’s Fellowship Edinburgh University 2014-19: Fixed term Researcher competition Rome University Tor Vergata
2016-present: Member of Interuniversity Institute of Myology (IIM) Scientific commitee 2019-22: Tenure track Researcher competition Rome University Tor Vergata E. CONTRIBUTION TO SCIENCE
His research interests during his professional life have been fascinated by regenerative phenomena. Muscle satellite cells were originally described in amphibians, but just as bystander cells without regenerative potential; in fact, amphibians muscle regeneration was ascribed to budding myoblasts (reentering cell cycle) from undamaged myofibers. During his PhD training (in the Prof. Slack laboratory) by exploiting a transgenic X. laevis model, he revealed the ability of resident stem cells (muscle satellite cells) to regenerate tail muscles, getting the basis for muscle satellite cells dependent myofiber regeneration in amphibians and thus demonstrating previously unappreciated analogy between amphibian and mammalian muscle regeneration (Gargioli and Slack, 2004). During his PostDoc research period, his interest has been attracted by muscle modifications in a dystrophic mouse model (alpha Sarcoglycan KO) at advanced stages of the disease (12 months old). So, he used tendon fibroblasts, engineered to produce angiogenic factors (Placental derived Growth Factor, PlGF and metalloproteases (MMP9) to rescue old dystrophic muscle, succeeding in ameliorating muscle environment, reducing sclerosis and restoring microcirculation. These modifications allowed efficient cell therapy in old dystrophic mice, thus opening the possibility to extend new therapies to currently untreatable patients (Gargioli et al., 2008). More recently being part of Angioscaff FP7 large scale European Project scheme, he focused the attention on skeletal muscle tissue engineering in order to promote muscle regeneration and engineered artificial muscle construction exploiting biomaterial technology. Thus, using vessel associated muscle progenitor cells, so called mesonagioblast (Mabs, in combination with biomimetic matrix (PEG-Fibrinogen PF, he investigated artificial muscle construction carrying out tissue engineering approaches:
1) in vivo experiments conducted in a muscle injury mouse model (cardiotoxin crushed) using PF as carrier for Mabs injection demonstrated increasing of transplanted cell survival, an ameliorated cell engraftment into injected muscles and overall PF showed a remarkable influence to improve integration and fusion of injected cells with host muscle forming hybrid regenerating and mature fibers (Fuoco et al., 2012);
2) Further above cited results he poured one’s energies into skeletal muscle reconstruction, thus employing the same technology he was able to reconstruct a normal, complete and functional TA after massive ablation (90% of muscle dislodged) (Fuoco et al., 2015).
Recently, increasingly the attention about tissue engineering, he began to investigate new myogenic stem cell populations and new technologies in order to enhance architectural and cellular complexity of artificial tissue. Thus, in collaboration with Prof. Madeddu at Bristol University he settled the isolation and characterization of perivascular myogenic precursor, namely pericytes, showing amazing capabilities in terms of proliferation and over all muscle differentiation. Furthermore, revealing a considerable role in supporting endothelial cells during angiogenesis (Fuoco et al., 2014; Vono et al., 2016). Besides collaborating with Dr. Costantini group at Institute of Physical Chemistry, Polish Academy of Science at Warsaw, he started to explore the possibility to exploit new technologies to ameliorate tendon tissue engineering (Testa et al.,2017) and skeletal muscle tissue engineering employing 3D printing techniques (Costantini et al., 2017).
F. Teaching activity
2014-present: Introduction to Genetic, Course of Pharmacy, Dipartimento di Biologia, Università di Roma “Tor Vergata”.
2023-present: Stem Cell Biotechnologies, Course of Biotechnology, Dipartimento di Biologia, Università di Roma “Tor Vergata”.
2014-2020: Comparative Anatomy, Course of Biological Science, Dipartimento di Biologia, Università di Roma “Tor Vergata”.
G. MAIN RESEARCH GRANTS (last 10 years)
2023-25 PI of MUR-PRIN Project (Systems vaccinology and innovative immunological approaches to investigate the impact of biological sex on COVID-19 mRNA vaccine immunogenicity, reactogenicity, and safety).
2021-23: Research Unit PO FESR LAZIO 2014/2020 “Lazio Innova”: BIOPMEAT. 2019-22: Coordinator and PI of RicostruzionE del tesSUto Muscolare scheletricO on mio-strutture stampate in 3D “RESUMO”Italian Ministry of Defense, PNRM (Piano Nazionale Ricerca Militare)
2019-22: PI of MIUR-PRIN Project (3D Muscle-Tendon Unit Modelling for Unravelling Tissue Crosstalk in Muscular Dystrophies and Aging).
2016-19: PI of MIUR-PRIN Project (Targeting autophagy in myogenic cells to counteract muscle aging and neuromuscular diseases).
2015-18: PI of Developing an artificial muscle tissues system as a platform to screen and test in vivo novel pharmacological therapies for muscular dystrophies patients, Tor Vergata Uncovering excellence funding scheme.
2011-14: PI of Novel strategies for the cell therapy of muscular dystrophies: reversible immortalization of human mesoangioblast. Fondazione Roma
2010-11: PI of Prototype validation support grant from the Angioscaff large scale FP7 collaborative project on angiogenesis and tissue engineering.
H. KEY PUBLICATIONS 1. Gargioli C. and Slack J.M.W. Cell lineage tracing during Xenopus tail regeneration. Development 2004 Jun; 131 (11): 2669-79 2. Gargioli C, Coletta M, De Grandis F, Cannata SM, and Cossu G. PlGF-MMP9 expressing cells restore microcirculation and efficacy of cell therapy in old dystrophic muscle. Nat Med. 2008 Sep 14(9):97 3. Fuoco C, Biondo A, Salvatori ML, Shapira-Schweitzer K, Santoleri S, Bernardini S, Cannata S, Seliktar D, Cossu G and Gargioli C.Injectable PEG-fibrinogen improves survival and differentiation of transplanted myogenic progenitors in acute and chronic skeletal muscle degeneration. Skelet Muscle 2012; 26;2(1):24. 4. Fuoco C,Sangalli E, Vono R, Testa S, Sacchetti B, Bernardini S, Madeddu P, Cesareni G, Seliktar D,Rizzi R, Bearzi C, Cannata S M, Spinetti Gand Gargioli C.3D hydrogel environment rejuvenates aged pericytes for skeletal muscle tissue engineering. Front Physiol. 2014 May 30;5:203. 5. Fuoco C, Biondo A, Longa E, Mascaro A, Shapira-Schweitzer K, Salvatori M L, Santoleri S, Testa S, Bernardini S, Cannata S M, Bottinelli R, Seliktar D, Cossu G and Gargioli C. In vivo generation of an entire, functional skeletal muscle.EMBO Mol Med. 2015 Feb 25. pii: e201404062
6. Vono R, Fuoco C, Testa S, Pirrò S, Maselli D, Mc Collough DF, Sangalli E, Pintus G, Giordo R, Finzi G, Sessa F, Cardani R, Gotti A, Losa S, Cesareni G, Rizzi R, Bearzi C, Cannata S, Spinetti G, Gargioli C, Madeddu P. Activation of the Pro-Oxidant PKCβII-p66Shc Signaling Pathway Contributes to Pericyte Dysfunction in Skeletal Muscles of Diabetic Patients with Critical Limb Ischemia.Diabetes. 2016 Sep 6. pii: db160248. 7. Testa S, Costantini M, Bernardini S, Trombetta M, Seliktar D, Cannata S, Rainer A and Gargioli C.Combination of biochemical and mechanical cues for tendon tissue engineering. J Cell Mol Med. 2017 May 4. 8. Costantini M, Testa S, Mozetic P, Barbetta A, Fornaretti E, Tamiro F, Jaroszewicz J, SÌwięszkowski W, Trombetta M, Seliktar D, Garstecki P, Cesareni G, Cannata S, Rainer A and Gargioli C.Microfluidically enhanced 3D bioprinting of highly aligned hydrogel structures for in vitro and in vivo fabrication of artificial muscle tissue. Biomaterials. 2017 Jul;131:98-110. 9. Errico V, Arrabito G, Fornetti E, Fuoco C, Testa S, Saggio G, Rufini S, Cannata S, Desideri A, Falconi C, Gargioli C. High-Density ZnO Nanowires as a Reversible Myogenic-Differentiation Switch. ACS Appl Mater Interfaces. 2018 Apr 25;10(16):14097-14107.
10. Testa S, Riera CS, Fornetti E, Riccio F, Fuoco C, Bernardini S, Baldi J, Costantini M, Foddai ML, Cannata S, Gargioli C. Skeletal Muscle-Derived Human Mesenchymal Stem Cells: Influence of Different Culture Conditions on Proliferative and Myogenic Capabilities. Front Physiol. 2020 Sep 16;11:553198.
11. Costantini M, Testa S, Fornetti E, Fuoco C, Sanchez Riera C, Nie M, Bernardini S, Rainer A, Baldi J, Zoccali C, Biagini R, Castagnoli L, Vitiello L, Blaauw B, Seliktar D, Święszkowski W, Garstecki P, Takeuchi S, Cesareni G, Cannata S, Gargioli C. Biofabricating murine and human myo-substitutes for rapid volumetric muscle loss restoration. EMBO Mol Med. 2021 Feb 15:e12778.
12. Fornetti E, Testa S, De Paolis F, Fuoco C, Bernardini S, Pozo Devoto V, Stokin G B, Giannitelli S M, Rainer A, Bigot A, Zoccali C, Baldi J, Sandonà D, Rizzi R, Bearzi C, Forte G, Cannata S, Gargioli C.Dystrophic Muscle Affects Motoneuron Axon Outgrowth and NMJ Assembly. Advanced Materials Technologies 2022 March.
13. Reggio A, De Paolis F, Bousselmi S, Cicciarelli F, Bernardini S, Rainer A, Seliktar D, Testa S, Cirillo C, Grumati P, Cannata S, Fuoco C, Gargioli C. A 3D adipogenesis platform to study the fate of fibro/adipogenic progenitors in muscular dystrophies. Dis Model Mech. 2023 Jun 1;16(6)
14. De Paolis F, Testa S, Guarnaccia G, Reggio A, Fornetti E, Cicciarelli F, Deodati R, Bernardini S, Peluso D, Baldi J, Biagini R, Bellisari FC, Izzo A, Sgalambro F, Arrigoni F, Rizzo F, Cannata S, Sciarra T, Fuoco C, Gargioli C. Long-term longitudinal study on swine VML model. Biol Direct. 2023 Jul 31;18(1):42.
15. Fornetti E, De Paolis F, Fuoco C, Bernardini S, Giannitelli SM, Rainer A, Seliktar D, Magdinier F, Baldi J, Biagini R, Cannata S, Testa S, Gargioli C.A novel extrusion-based 3D bioprinting system for skeletal muscle tissue engineering. Biofabrication. 2023 Feb 3;15(2).